22184-41-4

Basic information

• Product Name: 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine, 6-(4-bromophenyl)-
• CAS NO: 22184-41-4
• Molecular Formula: C10H7BrN4S
• Molecular Weight: 295.162
• Mol File: 22184-41-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine, 6-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine, 6-(4-bromophenyl)-(22184-41-4)
• EPA Substance Registry System: 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine, 6-(4-bromophenyl)-(22184-41-4)

Safety Data

• Hazardous Substances Data: 22184-41-4(Hazardous Substances Data)

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 149-73-5 trimethyl orthoformate 
• 4343-75-3 4-amino-3-mercapto-1,2,4-triazole 
• 122-51-0 orthoformic acid triethyl ester 
• 62467-73-6 5-(4-bromo-phenyl)-3,6-dihydro-[1,3,4]thiadiazin-2-one hydrazone 

Relevant articles and documents

Effective synthesis of 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines

[Figure not available: see fulltext.] A highly effective method for the preparation of 7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines was developed on the basis of condensation reaction between aryl(hetaryl) α-bromo ketones and commercially available thiocarbohydrazide, followed by treatment of the obtained 2-hydrazinyl-6H-1,3,4-thiadiazine hydrobromides with ortho esters in the presence of trifluoroacetic acid under mild conditions.

CONDENSED SYSTEMS BASED ON 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLE

1,2,4-Triazolo-1,3,4-thiadiazines, hydrazones, and β-thio adducts were obtained by reactions of 4-amino-3-mercapto-1,2,4-triazole with ω-bromoacetophenones, aldehydes, and α,β-unsaturated ketones.Conditions that promote the cyclocondensation of the