22184-99-2

Usage

Uses

Used in Pharmaceutical Industry:
3-(PIPERIDINOSULFONYL)ANILINE is used as a chemical intermediate for the synthesis of various drugs and other biologically active compounds, leveraging its unique structural features and reactivity in organic synthesis to contribute to the development of new pharmaceuticals.
Used in Dye and Pigment Production:
3-(PIPERIDINOSULFONYL)ANILINE is used as a building block in the production of dyes and pigments, where its structural properties can be utilized to create a range of colorants for different applications.
Further Research:
3-(PIPERIDINOSULFONYL)ANILINE is a molecule with potential applications and biological activities that are not yet fully understood. It requires additional research to explore its full capabilities and to identify new uses across various industries.

InChI:InChI=1/C11H16N2O2S/c12-10-5-4-6-11(9-10)16(14,15)13-7-2-1-3-8-13/h4-6,9H,1-3,7-8,12H2

Upstream product

• 91619-31-7 1-((3-nitrophenyl)sulfonyl)piperidine 
• 110-89-4 piperidine 
• 121-51-7 3-nitrobenzenesulphonyl chloride 

Downstream Products

• 608523-46-2 6-[3-(1-Piperidinesulfonyl)phenylazo]-pyridoxal-5-phosphate 
• 936092-54-5 5-methyl-N₂-[3-(piperidine-1-sulfonyl)-phenyl]-pyrimidine-2,4-diamine 
• 1019851-70-7 1-(3-benzylaminophenylsulfonyl)piperidine 
• 379255-31-9 2-chloro-N-[3-(piperidinyl-1-sulfonyl)phenyl]acetamide 
• 1363143-00-3 1-[3-(piperidine-1-sulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea 

Relevant academic research and scientific papers

FLT3 RECEPTOR ANTAGONISTS

The invention pertains to novel FLT3receptor antagonists of general formula (1). The compounds are useful for the treatment or the prevention of pain disorders, cancer and autoimmune diseases.

Synthesis and anticandidal activity of azole-containing sulfonamides

Twenty five benzenesulfonamides containing one imidazole or triazole ring, or two imidazole or triazole rings have been synthesized and evaluated as anticandidal agents. The most active compounds were 5c, 6b, 6c, 6e, and 17b, which exhibited MIC values of 4.55-24.39 mM depending on the clinical isolate. Comparing imidazole to triazole derivatives did not show a clear effect on activity. Compounds containing a N-benzyl group also showed no clear evidence on activity given the fact that they have an extra aromatic ring. Secondary sulfonamides, 5l, 5m, and 5n showed activities that were proportional to their lipophilicity. The activities of N-aryl-substituted derivatives 5j, 5k, 5l, 5m, 5n, and 6j were also proportional to their lipophilicity. Halogenation enhanced the activity as a result of improvement of lipophilicity. The presence of two imidazole or triazole rings in the same compound did not show a clear enhancement of activity.

GLUCAGON ANTAGONISTS/INVERSE AGONISTS

A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-