Cas 22187-22-0,1-oxo-2-(4-methoxylphenyl)-1,2-dihydrobenzimidazo[1,2-d][1,2,4]triazine-4-carbonitrile

22187-22-0

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Basic information

Product Name: 1-oxo-2-(4-methoxylphenyl)-1,2-dihydrobenzimidazo[1,2-d][1,2,4]triazine-4-carbonitrile
Synonyms:
CAS NO:22187-22-0
Molecular Formula:
Molecular Weight: 317.307
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-oxo-2-(4-methoxylphenyl)-1,2-dihydrobenzimidazo[1,2-d][1,2,4]triazine-4-carbonitrile(CAS DataBase Reference)
NIST Chemistry Reference: 1-oxo-2-(4-methoxylphenyl)-1,2-dihydrobenzimidazo[1,2-d][1,2,4]triazine-4-carbonitrile(22187-22-0)
EPA Substance Registry System: 1-oxo-2-(4-methoxylphenyl)-1,2-dihydrobenzimidazo[1,2-d][1,2,4]triazine-4-carbonitrile(22187-22-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 22187-22-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 22187-22-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,8 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 22187-22:
(7*2)+(6*2)+(5*1)+(4*8)+(3*7)+(2*2)+(1*2)=90
90 % 10 = 0
So 22187-22-0 is a valid CAS Registry Number.

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22187-22-0Relevant academic research and scientific papers

Synthesis of new heterocyclic compounds containing benzimidazole moiety as inhibitors of breast cancer cell growth

Tantawy, Atif,Barghash, Alaa-Eldin,Badr, Sahar,Gomaa, Rania

, p. 125 - 131 (2013)

A series of new benzimidazole derivatives, namely 2-acylbenzimidazoles 2- 9, a dihydroquinoxaline 10, a benzoxazine 11, quinolines 13 - 15 and fused 1,2,4-triazines 17 - 24 were synthesized. Structure elucidation of the compounds was conducted using IR, 1H NMR, 13C NMR, mass spectral data and elemental analysis. These products were evaluated for in vitro antitumor activity against MCF7 cell line (human breast cancer). Compounds 13 - 15 and 24 manifested significant antitumor activity.

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