221878-99-5Relevant academic research and scientific papers
Highly efficient double enantioselection by lipase-catalyzed transesterification of (R,S)-carboxylic acid vinyl esters with (RS)-1- phenylethanol
Yang, Hong,Henke, Erik,Bornscheuer, Uwe T.
, p. 957 - 960 (2007/10/03)
Transesterification of the title compounds using lipase B from Candida antarctica in toluene afforded the corresponding esters in good to excellent diastereomeric excess. (R)-2-Phenylpropionic acid-(R)-1-phenethyl ester 4 was isolated in 45% yield and 64%
