222022-70-0Relevant articles and documents
A novel asymmetric synthesis of 2,5-dialkylpyrrolidines
Daley, Valerie,D'Angelo, Jean,Cave, Christian,Mahuteau, Jacqueline,Chiaroni, Angele,Riche, Claude
, p. 1657 - 1660 (1999)
ZnCl2-promoted cyclization of enamino ester 8 furnished a 1.5:1 mixture of pyrrolidines 9 and 10. NaBH4-reduction of this mixture gave cis and trans-2,5-dialkylpyrrolidines 12 and 13 in the ratio 2:1. The latter derivative was obtain