222174-78-9

Upstream product

• 79898-19-4 (2R,3S)-3-phenyloxiranecarboxylic acid 
• 174729-14-7 13-O-((2S,3R)-3-bromo-2-hydroxy-3-phenylpropionyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin 
• 174847-58-6 C₄₄H₄₄Cl₆O₁₆ 
• 115794-67-7 methyl (2R,3S)-3-phenylglycidate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 222171-66-6 C₄₄H₄₅Cl₆N₃O₁₆ 

Relevant academic research and scientific papers

Synthesis of taxoids 4. Novel and versatile methods for preparation of new taxoids by employing cis- or trans-phenyl glycidic acid

A novel route to the synthesis of docetaxel using esterification of (2R,3R)-or (2R,3S)-glycidic acid with 7,10-bis-O-(2,2,2- trichloroethoxycarbonyl)-10-deacetylbaccatin III is described. Related novel taxoids which have new side chains were synthesized from these synthetic intermediates.