22228-23-5 Usage
Uses
Used in Organic Synthesis:
Spiro[cyclopropane-1,2'-indan]-1'-one is used as a synthetic intermediate for the preparation of complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the synthesis of a wide range of compounds with potential applications in various fields.
Used in Photochemical Reactions:
In the field of photochemistry, Spiro[cyclopropane-1,2'-indan]-1'-one is used as a precursor for the generation of reactive intermediates. It can be irradiated in methylcyclohexane or EtOH/MeOH glasses at 77K to produce (E)-2-Ethylidene-1-indanone, which is an important intermediate for further chemical transformations.
Used in Pharmaceutical Industry:
Spiro[cyclopropane-1,2'-indan]-1'-one is used as a key building block in the development of pharmaceutical compounds. Its ability to participate in various chemical reactions makes it a valuable asset in the synthesis of new drugs with potential therapeutic applications.
Used in Materials Science:
In materials science, Spiro[cyclopropane-1,2'-indan]-1'-one is utilized in the synthesis of novel materials with unique properties. Its involvement in the formation of complex molecular structures can lead to the development of advanced materials with applications in various industries, such as electronics, coatings, and polymers.
Check Digit Verification of cas no
The CAS Registry Mumber 22228-23-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,2 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22228-23:
(7*2)+(6*2)+(5*2)+(4*2)+(3*8)+(2*2)+(1*3)=75
75 % 10 = 5
So 22228-23-5 is a valid CAS Registry Number.
22228-23-5Relevant academic research and scientific papers
Substituent Effect in Solvolysis of Spiro-1'-yl p-Nitrobenzoate
Ohkata, Katsuo,Akiyama, Masaki,Wada, Kenshi,Sakaue, Shun,Toda, Yoshiko,Hanafusa, Terukiyo
, p. 2517 - 2520 (2007/10/02)
The preparation of a series of substituted spiro-1'-yl p-nitrobenzoates (4a-g) is described.The solvolysis rate constant is k = 8.53 * 10-5 s-1 at 25 deg C in 80percent aqueous acetone for the unsaturated derivative (4e) and is relatively high in comparison with the related secondary systems.The Hammett treatment (ρ?+) gives a straight line and the ρ value (-3.33) is more negative than that (-2.11) of 3,4-benzotricyclo1,6>-dec-3-en-2-anti-yl p-nitrobenzoate (1).On the basis of the results, it can be considered that the mesomeric transmission of substituent effect is very weak in 1 relative to 4.
