2223-71-4Relevant articles and documents
Construction of Distant Stereocenters by Enantioselective Desymmetrizing Carbonyl-Ene Reaction
Luo, Weiwei,Lin, Lili,Zhang, Yu,Liu, Xiaohua,Feng, Xiaoming
, p. 3374 - 3377 (2017/07/15)
An efficient desymmetrizing carbonyl-ene reaction of 1-substituted 4-methylenecyclohexanes with glyoxal derivatives was thus executed by a chiral N,N′-dioxide/NiII catalyst, providing facile access to cyclohexene derivatives bearing two remote 1,6-related stereocenters. This distal stereocontrol methodology originates from the efficient interaction between the catalyst with enophiles, discrimination of the two chair conformations of olefinic components, and the intrinsic six-membered transition-state structure of ene process.
A remarkable iodine-catalyzed protection of carbonyl compounds
Banik, Bimal K.,Chapa, Marin,Marquez, Jocabed,Cardona, Magda
, p. 2341 - 2343 (2007/10/03)
We report here a remarkably simple molecular iodine-catalyzed protection method for various carbonyl compounds as ketals in a general reaction. The iodine-catalyzed reaction of mandelic acid and lactic acid with several aldehydes has furnished a highly diastereoselective synthesis of cis and trans dioxolanones.
An efficient procedure for the preparation of cyclic ketals and thioketals catalyzed by zirconium sulfophenyl phosphonate
Curini,Epifano,Marcotullio,Rosati
, p. 1182 - 1184 (2007/10/03)
A convenient method for the preparation of cyclic ketals and thioketals using zirconium sulfophenyl phosphonate as catalyst is described.