22242-79-1Relevant academic research and scientific papers
Michael addition of aromatic heterocyclic compounds to α,β-unsaturated ketones. 3-Oxoalkylation of furans, indoles and thiophenes.
Dujardin, Gilles,Poirier, Jean-Marie
, p. 900 - 909 (2007/10/02)
The Lewis-acid catalyzed Michael-type addition of aromatic heterocyclic compounds, such as furans, indoles and thiophenes, to α,β-unsaturated ketones (including methyl vinyl ketone) was performed in mild conditions in the presence of boron trifluoride etherate and an alcohol.Rosethiophene was prepared in a synthesis involving a few steps. - Keywords: Michael addition / boron trifluoride etherate / but-3-ene-2-one / 3-oxoalkylation / rosethiophene
α,β-UNSATURATED KETONES IN SUBSTITUTIVE ADDITION WITH 2-ALKYLFURANS AND SOME TRANSFORMATIONS OF THE REACTION PRODUCTS
Akhmedov, Sh. T.,Sadykhov, N. S.,Akhmedova, R. Sh.,Zefirov, N. S.
, p. 1158 - 1161 (2007/10/02)
The substitutive addition of cyclic α,β-unsaturated ketones with 2-alkylfurans proceeds in the presence of catalytic amounts of sulfuric acid to give the corresponding furyl ketones.The latter were converted by Kishner reduction to cycloalkylfurans and were also converted to ethyleneketals, which form adducts with maleic anhydride.
