22245-90-5

Upstream product

• 1312005-59-6 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one 
• 53841-99-9 7-Brom-1,3,4,5-tetrahydro-2H-benzazepin-2-on 
• 4424-80-0 2,3,4,5-tetrahydro-1H-1-benzo[b]azepin-2-one 

Downstream Products

• 1294010-39-1 C₁₇H₁₆ClNO₂ 
• 22245-89-2 7-methoxy-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 
• 1228698-86-9 C₁₇H₁₆ClNO₂ 
• 1294010-40-4 C₁₇H₁₆ClNO₂ 
• 1294010-44-8 C₁₇H₁₆BrNO₂ 
• 1294010-43-7 C₁₈H₁₉NO₂ 
• 1228698-85-8 C₁₇H₁₆FNO₂ 
• 1294010-42-6 C₁₇H₁₆FNO₂ 
• 1294010-41-5 C₁₇H₁₆FNO₂ 
• 156938-71-5 7-Benzyloxy-1,3,4,5-tetrahydro-2H-benzazepin-2-on 
• 1338454-32-2 8-(4-methylbenzyloxy)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a]azepine 
• 1338454-27-5 8-(4-bromobenzyloxy)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a]azepine 
• 1338454-23-1 8-(4-fluorobenzyloxy)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a]azepine 
• 1338454-19-5 8-(3-fluorobenzyloxy)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a]azepine 

Relevant academic research and scientific papers

Triazole derivative having HSP90 (Heat Shock Protein) inhibiting activity, as well as preparation method and application of triazole derivative

The invention discloses a triazole derivative having an HSP90 (Heat Shock Protein) inhibiting activity, as well as a preparation method and an application of the triazole derivative. Specifically, the invention relates to the triazole derivative having a structure as shown in a formula (I), a stereisomer of the triazole derivative and a pharmaceutically acceptable salt, wherein the definition of each substituent group in the formula (I) and the definition in a description are the same. The compound with a novel structure has the HSP90 inhibiting activity, can be used to cure cancers, neurodegenerative disorders, inflammation diseases, autoimmune diseases, ischemic brain injuries and the like, and has a broad application prospect.