22245-89-2

Basic information

• Product Name: 1,3,4,5-TETRAHYDRO-7-METHOXY-2H-1-BENZAZEPIN-2-ONE
• Synonyms: 7-METHOXY-1,3,4,5-TETRAHYDRO-BENZO[B]AZEPIN-2-ONE;2H-1-BENZAZEPIN-2-ONE, 1,3,4,5-TETRAHYDRO-7-METHOXY-;1,3,4,5-TETRAHYDRO-7-METHOXY-2H-1-BENZAZEPIN-2-ONE;7-Methoxy-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one;7-methoxy-1,3,4,5-tetrahydro-1-benzazepin-2-one;7-METHOXY-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-2-ONE
• CAS NO: 22245-89-2
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Mol File: 22245-89-2.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 385.1°C at 760 mmHg
• Flash Point: 186.7°C
• Appearance: /
• Density: 1.121g/cm³
• Vapor Pressure: 3.89E-06mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 1,3,4,5-TETRAHYDRO-7-METHOXY-2H-1-BENZAZEPIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4,5-TETRAHYDRO-7-METHOXY-2H-1-BENZAZEPIN-2-ONE(22245-89-2)
• EPA Substance Registry System: 1,3,4,5-TETRAHYDRO-7-METHOXY-2H-1-BENZAZEPIN-2-ONE(22245-89-2)

Safety Data

• Hazardous Substances Data: 22245-89-2(Hazardous Substances Data)

Usage

General Description

1,3,4,5-tetrahydro-7-methoxy-2H-1-benzazepin-2-one, also known as methoxyneflazin, is a chemical compound with molecular formula C12H15NO2. It is used in the field of pharmaceuticals and is known for its potential application as a CNS depressant and an antidepressant. The compound has a bicyclic structure and contains a benzene ring fused to a seven-membered nitrogen-containing ring. Its specific mechanism of action and potential therapeutic uses are still under research, and it is not widely used in clinical practice at this time. The compound's chemical properties and potential pharmacological effects make it of interest for further study in the field of drug development and neuropharmacology.

InChI:InChI=1/C11H13NO2/c1-14-9-5-6-10-8(7-9)3-2-4-11(13)12-10/h5-7H,2-4H2,1H3,(H,12,13)

Upstream product

• 201230-82-2 carbon monoxide 
• 68267-68-5 2-allyl-4-methoxyaniline 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 90817-92-8 C₁₈H₁₉NO₄S 
• 22245-90-5 1,3,4,5-tetrahydro-7-hydroxy-2H-1-benzazepin-2-one 
• 54951-36-9 (1E)-6-methoxy-3,4-dihydronaphthalen-1(2H)-one oxime 
• 436155-78-1 phenyl (7-methoxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)carbamate 
• 436155-56-5 phenyl 2-[4-(3-methoxyphenyl)butanoyl]hydrazinecarboxylate 
• 952007-72-6 4-(3-methoxyphenyl)butanoyl chloride 
• 24743-11-1 4-(m-methoxyphenyl)butanoic acid 
• 436155-91-8 1-amino-7-methoxy-1,3,4,5-tetrahydrobenzo[b]azepin-2-one 
• 54951-36-9 6-methoxy-1-tetralone oxime 
• 214279-40-0 3-iodo-4-nitroanisol 
• 1536478-81-5 N-(2-bromo-4-methoxyphenyl)formamide 

Downstream Products

• 46180-98-7 7-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine 
• 1427309-66-7 1-phenyl-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one 
• 211761-53-4 [3-(3-azido-7-methoxy-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-ylmethyl)-phenyl]-carbamic acid tert-butyl ester 
• 213664-70-1 3-amino-1-N-(3-(N'-(tert-butoxycarbonyl)amino)benzyl)-7-methoxy-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 
• 250131-90-9 (3-benzyloxycarbonylamino-7-methoxy-2-oxo-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetic acid tert-butyl ester 

Relevant articles and documents

Design, synthesis, and opioid receptor binding of some novel benzazepine constrained leucine enkephalin mimetics

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High-yield method for the preparation of 1,3,4,5-tetrahydro-7-methoxy-2 H-1-benzazepin-2-one with excellent regio-and stereoselectivity

We have surveyed the effects of different acid catalysts, reaction times, and temperatures on the yield, regioselectivity, and stereoselectivity and calculated the ketoxime isomerization and activation energy of the title compound. A facile synthetic proc