22246-71-5

Basic information

• Product Name: 8-Methoxy-2,3,4,5-tetrahydrobenzo[c]azepin-1-one
• Synonyms: 8-METHOXY-2,3,4,5-TETRAHYDRO-BENZO[C]AZEPIN-1-ONE;4-Methoxy-2,3,5,6-tetrafluorobenzoicacid;1H-2-Benzazepin-1-one, 2,3,4,5-tetrahydro-8-methoxy-;8-methoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one;8-methoxy-2,3,4,5-tetrahydro-2-benzazepin-1-one
• CAS NO: 22246-71-5
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• EINECS: 604-604-1
• Mol File: 22246-71-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 440.156 °C at 760 mmHg
• Flash Point: 219.999 °C
• Appearance: /
• Density: 1.121 g/cm³
• Vapor Pressure: 6.02E-08mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 8-Methoxy-2,3,4,5-tetrahydrobenzo[c]azepin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Methoxy-2,3,4,5-tetrahydrobenzo[c]azepin-1-one(22246-71-5)
• EPA Substance Registry System: 8-Methoxy-2,3,4,5-tetrahydrobenzo[c]azepin-1-one(22246-71-5)

Safety Data

• Hazardous Substances Data: 22246-71-5(Hazardous Substances Data)

Usage

General Description

8-Methoxy-2,3,4,5-tetrahydrobenzo[c]azepin-1-one is a chemical compound with a molecular formula C11H13NO2. It is a white to off-white crystalline powder that is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and bioactive compounds. This chemical is known for its potential to exhibit various pharmacological activities, including antipsychotic, anticonvulsant, and sedative properties, making it a valuable intermediate in the development of new medications. Additionally, it has been studied for its potential role in the treatment of neurological disorders and mental health conditions. However, further research is needed to fully understand the scope of its therapeutic applications.

InChI:InChI=1/C11H13NO2/c1-14-9-5-4-8-3-2-6-12-11(13)10(8)7-9/h4-5,7H,2-3,6H2,1H3,(H,12,13)

Upstream product

• 6836-19-7 7-Methoxy-1-tetralone 
• 20175-97-7 7-methoxy-3,4-dihydronaphthalen-1(2H)-one oxime 

Downstream Products

• 247133-22-8 8-Methoxy-2,3,4,5-tetrahydro-1H-benz[c]azepine 
• 374813-35-1 2,3,4,5-tetrahydro-1H-2-benzazepin-8-ol hydrobromide 
• 247133-24-0 8-hydroxy-2,3,4,5-tetrahydro-1H-benz[c]azepine-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthesis and biological evaluation of N-alkylated 8-oxybenz[c]azepine derivatives as selective PPARδ agonists

We describe the discovery of small molecule benzazepine derivatives as agonists of human peroxisome proliferator-activated receptor δ (PPARδ) that displayed excellent selectivity over the PPARα and PPARγ subtypes. Compound 8 displayed good PK in the rat a

NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

Compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein X, R1, R2, R3, R4 and R5 are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Amidine compounds

A compound of the formula [I] wherein R1, R2and R3are the same or different and each is hydrogen atom, wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof. The compound of the presen