22246-79-3

Usage

Uses

Used in Pharmaceutical Industry:
8-NITRO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPIN-2-ONE is used as an antipsychotic agent for its potential to treat various central nervous system disorders. Its action as a selective antagonist at dopamine D1 and D5 receptors contributes to its effectiveness in managing psychotic symptoms.
Used in Allergy Treatment:
8-NITRO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPIN-2-ONE is used as an antiallergic agent due to its pharmacological properties, which may help in alleviating allergic reactions and related symptoms.
Used in Neurological Disorders Treatment:
8-NITRO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPIN-2-ONE is used as a therapeutic agent for the treatment of various central nervous system disorders, leveraging its anti-inflammatory effects and potential to modulate neurotransmitter receptor activity.
Used in Research and Development:
8-NITRO-1,3,4,5-TETRAHYDRO-2H-1-BENZAZEPIN-2-ONE is used as a research compound for studying its pharmacological effects, receptor interactions, and potential applications in drug development for treating neurological and psychiatric conditions.

InChI:InChI=1/C10H10N2O3/c13-10-3-1-2-7-4-5-8(12(14)15)6-9(7)11-10/h4-6H,1-3H2,(H,11,13)

Upstream product

• 4424-80-0 2,3,4,5-tetrahydro-1H-1-benzo[b]azepin-2-one 
• 871897-49-3 4-(2-amino-4-nitro-phenyl)-butyric acid 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 56182-28-6 4-(2-aminophenyl)butanoic acid hydrochloride 
• 67104-86-3 (1E)-N-hydroxy-7-nitro-3,4-dihydronaphthalen-1(2H)-imine 
• 40353-34-2 7-nitro-3,4-dihydro-2H-naphthalen-1-one 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 74117-98-9 4-(2-amino-phenyl)-butyric acid ethyl ester 
• 3349-64-2 1-tetralone oxime 

Downstream Products

• 1022971-27-2 2-{5-chloro-2-[1-(2-methoxy-ethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino]-pyrimidin-4-ylamino}-3-fluoro-N-methyl-benzamide 
• 22246-76-0 8-amino-4,5-dihydro-1H-benzo[b]-azepin-2(3H)-one 
• 144583-94-8 1-methyl-8-amino-2,3,4,5-tetrahydro-1H-benzo[b]azepin-2-one 

Relevant academic research and scientific papers

NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF

The present invention relates to compounds of formula (I): wherein R6 is —CONH2 or a —C(Rα)(Rβ)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.

NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF

The present invention relates to compounds of formula (I): wherein R6 is -CONH2 or a -C(Rα)(Rβ)(OH) group; R is a substituted phenyl or heteroaryl group; R7 is an optionally substituted aryl or heteroaryl group. Process for the preparation thereof and therapeutic use thereof.

Synthesis of 7-mercapto-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one

The synthesis of 7-mercapto-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one - a potential monomer for preparing network polymers - is reported.

Carboxamides and anilides

Described herein are compounds of the formula STR1 wherein R1 signifies hydrogen, lower-alkyl or a cation; R2 signifies hydrogen, lower-alkyl, lower-alkoxy or halogen; M signifies --CONH-- or --NHCO--; X and Y are each independently selected from the group consisting of >CR3 R4 and --CONR5 --; Z signifies >CR6 R7 ; R3, R4, R6 and R7 are each independently selected from the group consisting of hydrogen and lower-alkyl; R5 signifies alkyl; and n signifies 0, 1 or 2; provided that at least one of X or Y is --CONR5 -- which is bonded to the phenyl ring via the N atom. These compounds are useful in the treatment and prophylaxis of neoplasms, dermatoses and aging of the skin.