2226-49-5Relevant academic research and scientific papers
Generation and reactions of heteroaromatic lithium compounds by using in-line mixer in a continuous flow microreactor system at mild conditions
Liu, Binjie,Fan, Yong,Lv, Xiaoming,Liu, Xiaofeng,Yang, Yongtai,Jia, Yu
, p. 133 - 137 (2013/03/13)
A lithium-halogen exchange reaction procedure was applied to introduce electrophilic substituents to the heteroaromatics, which exhibited potential in the syntheses of pharmaceutical intermediates. In this contribution, generation and reactions of heteroa
Selective palladium-catalysed ipso arylation of α,α- disubstituted benzo[b]thien-2-ylmethanols with aryl bromides using PCy 3 as ligand
Biro, A. Beatrix,Kotschy, Andras
, p. 1364 - 1368 (2008/09/18)
α,α-Diphenylbenzo[b]thien-2-ylmethanol was treated with a series of aryl bromides in the presence of palladium(II) acetate and tricyclohexylphosphane to give the appropriate 2-aryl-benzo[b]thiophenes in good to excellent yield with concomitant formation o
The Tris(2-thienyl)methyl Cation Problem. A Nuclear Magnetic Resonance Spectroscopic Study
Abarca, Belen,Asensio, Gregorio,Ballesteros, Rafael,Varea, Teresa
, p. 3224 - 3229 (2007/10/02)
A series of homologues of the trityl cation obtained by total or partial substitution of the phenyl rings for 2- or 3-thienyl groups has been studied by 1H and 13C NMR.In general, the spectral parameters found follow the expected trends.However, a most unexpected effect is found in the transformation of tris(2-thienyl)carbinol (1d) into tris(2-thienyl)methyl cation (2d) , since the increase of the total chemical shift (ΔΣδ) associated with the ionization is as low as 105 ppm.To account for this observation, several hypotheses are discussed including the possibility of through-space charge delocalization by the three sulfur atoms and the interaction of the thiophene rings in an alternate conformation.
