2227-25-0Relevant articles and documents
Studies on the series of azoles and azines. 66. Synthesis, spectra and structure of 5-arylazo- and 5-arylideneamino-2,4,6-triaminopyrimidines and their 6-hydroxy analogs
Belodedova,Smorygo,Mirzoyan,Melik-Orandzhanyan,Studentsov,Ivin
, p. 538 - 545 (2007/10/02)
5-Arylazo and 5-arylideneamino-2,4,6-triaminopyrimidines and their 6-hydroxy analogs were obtained by azo coupling of 2,4,6-triamino- and 2,4-diamino-6-hydroxypyrimidines with aryldiazonium salts, and also by the reaction of benzaldehydes with 2,4,5,6-tetraamino- and 2,4,5-triamino-6-hydroxypyrimidines, respectively. According to spectral data, in solvents with different polarity, these compounds exist preferentially in the triamino- or diaminohydroxy form. The main paths of the mass spectrometric fragmentation of the compounds studied have been determined.
Potential folic acid antagonists. 5. Synthesis and dihydrofolate reductase inhibitory activities of 2-amino-4,6-substituted-5-arylazopyrimidines.
Chatterjee,Ludwig,Moran,Triggle,Wayne
, p. 1237 - 1238 (2007/10/08)
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