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N-{9-[5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(tert-butyl-dimethyl-silanyloxy)-4-oxo-tetrahydro-furan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-isobutyramide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

222725-67-9

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222725-67-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 222725-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,7,2 and 5 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 222725-67:
(8*2)+(7*2)+(6*2)+(5*7)+(4*2)+(3*5)+(2*6)+(1*7)=119
119 % 10 = 9
So 222725-67-9 is a valid CAS Registry Number.

222725-67-9Relevant academic research and scientific papers

Nuclease resistant hammerhead motif: From '5-ribo' to '3-ribo' model

Matulic-Adamic, Jasenka,Daniher, Andrew T.,Gonzalez, Carolyn,Beigelman, Leonid

, p. 157 - 160 (1999)

Previously developed '5-ribo' nuclease stabilized hammerhead motif was further refined by systematic incorporation of 1-(β-D-xylofuranosyl) adenine (xA) and 1-(β-D-xylofuranosyl) guanine (xG) in the place of conserved ribopurine residues of the catalytic core. Modified ribozymes substituted with xA at positions A15.1 and A6 demonstrated catalytic activity close to the parent stabilized ribozyme. Analogous guanosine substitutions at positions G5, G8 and G12 substantially lowered catalytic rates.

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