22278-75-7

Upstream product

• 3617-01-4 β-(4-chlorophenyl)pyruvic acid 
• 2231-57-4 Thiocarbohydrazide 
• 93634-55-0 (Z)-4-(4-chlorobenzylidene)-2-methyloxazol-5(4H)-one 
• 93634-55-0 2-methyl-4-(4-chlorobenzylidene)-4H-oxazol-5-one 
• 88681-63-4 2-acetamido-3-(4-chlorophenyl)acrylic acid 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 202651-01-2 4-{[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-amino}-6-(4-chloro-benzyl)-3-mercapto-4H-[1,2,4]triazin-5-one 
• 202650-99-5 6-(4-Chloro-benzyl)-3-mercapto-4-{[1-p-tolyl-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazin-5-one 
• 202651-00-1 6-(4-Chloro-benzyl)-3-mercapto-4-{[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazin-5-one 
• 202651-06-7 6-Benzo[1,3]dioxol-5-ylmethyl-3-mercapto-4-{[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazin-5-one 

Relevant academic research and scientific papers

Synthesis and antimicrobial activities of a new series of 4-S-[41-amino-51-oxo-61-substituted benzyl-41,51-dihydro-11,21,41-triazin-3-yl]mercaptoacetyl-3-arylsydnones

The synthesis of some 4-S-(41-amino-51-oxo-61-substituted benzyl-41,51-dihydro-11,21,41-triazin-3-yl)mercaptoacetyl-3-arylsydnones by the reaction of 3-aryl-4-bromoacetylsydnones with 6-substituted-4-amino-3-mercapto-1,2,4-triazin-5-ones is described. The IR, 1H NMR, mass spectra and elemental analysis characterized the newly synthesized compounds. The synthesized compounds were screened for their antimicrobial activity. All the compounds showed higher activity than that of standard drug during antimicrobial studies and the activity was comparable with the standard drug for antifungal activity.

Synthesis of some new fluorine containing thiadiazolotriazinones as potential antibacterial agents

2,4-dichloro-5-fluorophenyl, 4-fluoro-3-(Phenoxy)phenyl, 4-fluorophenyl groups are known pharmacophores and can be used in the synthesis of new biologically active molecules. Therefore, 4-amino-6-arylmethyl-3-mercapto-1,2,4- triazin5(4H)-ones 1 are conden

Studies on arylmethyltriazinone derivatives-Part II. Synthesis and antifungal properties of 2-aminomethyl-4-(arylidene)amino-6-arylmethyl-3-mercapto-1, 2,4-triazin-5(4H)-ones

The preparation of twenty new 2-aminomethyl-4-(arylidene)amino-6-arylmethyl-3-mercapto-1,2,4-triazin-5(4H)- ones(4) is described. The structural elucidation of all the compounds is carried out on the basis of analytical and spectral data. The newly synthesized compounds are evaluated for their antifungal activity against Candida albicans and Paecileomyces variotti.

Synthesis of biologically active 4-amino-6-arylmethyl-3-mercapto-1,2,4-triazin-5(4H)-ones and their Schiff bases

Three arylpyruvic acids 2 are condensed with thiocarbohydrazide (3) in aqueous ethanol to yield 4-amino-6-arylmethyl-3-mercapto-1,2,4-triazin-5(4H)-ones 4. In a modified method these title compounds 4 have also been prepared by direct condensation of the

Herbicidal agents

3-[HYDROGEN-, (UNSUBSTITUTED AND HALO, AMINO, NITRO, ALKYL, ALKANOYL, ALKOXY, ALKYLMERCAPTO, ARYLOXY AND/OR ARYL-MERCAPTO-SUBSTITUTED) ALIPHATIC-, CYCLOALIPHATIC-, ARALIPHATIC-, ARYL-, OR HETEROCYCLIC- -SUBSTITUTED OXY, MERCAPTO OR AMINO]4-[AMINO; MONO AND DI (UNSUBSTITUTED AND CYANO, HYDROXY AND/OR HALO-SUBSTITUTED) ALKYL- AND/OR ALKANOYL-AMINO; N-heterocyclic; or N-(unsubstituted and aryl, haloaryl, alkoxyaryl, nitroaryl and/or heterocyclic- substituted) alkylidene or cycloalkylidene]-6-[(unsubstituted and halo, nitro, carbo lower alkoxy, alkyl, alkoxy, alkylmercapto, aralkylmercapto, aryloxy and/or arylmercapto-substituted) aliphatic, cycloaliphatic, araliphatic, aryl, or heterocyclic]-1,2,4-triazine-5-ones, which possess herbicidal properties, and which may be produced by conventional methods.