222848-57-9

Upstream product

• 87-72-9 L-arabinofuranose 
• 372515-40-7 1-(2',3',4'-tri-O-benzoyl-α-L-lyxopyranosyl)thymine 
• 222848-50-2 1-{2',3'-O-[ethoxy(phenyl)methylidene]-α-L-lyxopyranosyl}thymine 
• 222848-40-0 1-(α-L-lyxopyranosyl)thymine 
• 372515-38-3 1',2',3',4'-tetra-O-benzoyl-L-lyxopyranose 
• 1663-61-2 triethoxymethylbenzene 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 253875-07-9 1-[2'-O-benzoyl-3'-O-((2-cyanoethoxy)(diisopropylamino)phosphino)-4'-O-((4'',4'''-dimethoxytriphenyl)methyl)-α-lyxopyranosyl-(1')]thymine 
• 222848-62-6 1-{3'-O-benzoyl-2'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-4'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-lyxopyranosyl}thymine 

Relevant academic research and scientific papers

Pentopyranosyl oligonucleotide systems: The α-L-lyxopyranosyl-(4′ → 2′)-oligonucleotide system

To determine whether the remarkable chemical properties of the pyranosyl isomer of RNA as an informational Watson-Crick base-pairing system are unique to the pentopyranosyl-(4′ → 2′)-oligonucleotide isomer derived from the RNA-building block D-ribose, studies on the entire family of diastereoisomeric pyranosyl-(4′ → 2′)-oligonucleotide systems deriving from D-ribose, L-lyxose, D-xylose, and L-arabinose were carried out. The result of these extended studies is unambiguous: not only pyranosyl-RNA, but all members of the pentopyranosyl-(4′ → 2′)-oligonucleotide family are highly efficient Watson-Crick base-pairing systems. Their synthesis and pairing properties will be described in a series of publications in this journal. The present paper describes the α-L-lyxopyranosyl-(4′ → 2′)-system.