222853-52-3Relevant academic research and scientific papers
Investigation of Masked N-Acyl-N-isocyanates: Support for Oxadiazolones as Blocked N-Isocyanate Precursors
Gagné-Monfette, William,Vincent-Rocan, Jean-Fran?ois,Lutes, Owen C.,O'Keefe, Geneviève F.,Jeanneret, Alexandria D. M.,Blanger, Claire,Ivanovich, Ryan A.,Beauchemin, André M.
, p. 14051 - 14056 (2021/09/14)
In contrast to carbon-substituted isocyanates that are common building blocks, N-substituted isocyanates remain underdeveloped and reports on their N-acyl derivatives (i. e. amido-isocyanates) are exceedingly rare. Herein, amido-isocyanates were investiga
Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease
Venkatraman, Shankar,Kong, Jian-she,Nimkar, Sanjay,Wang, Q. May,Aube, Jeffrey,Hanzlik, Robert P.
, p. 577 - 580 (2007/10/03)
A series of azapeptides was prepared and assessed as inhibitors of the human rhinovirus 3C protease. Boc-VLFaQ-OPh was a slow-turnover substrate that gave transient (ca. 1-2 h) inhibition as it underwent hydrolysis. Boc- VLFaG-OPh gave very slow but essen
