222854-81-1

Basic information

• Product Name: 1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(cyanomethyl)tetrahydro-9-hydroxy-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8S,9S,9aR)-
• Synonyms: 1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(cyanomethyl)tetrahydro-9-hydroxy-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8S,9S,9aR)-
• CAS NO: 222854-81-1
• Molecular Formula: C24H46 N2 O6 Si2
• Molecular Weight: 514.8
• Mol File: 222854-81-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(cyanomethyl)tetrahydro-9-hydroxy-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8S,9S,9aR)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(cyanomethyl)tetrahydro-9-hydroxy-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8S,9S,9aR)-(222854-81-1)
• EPA Substance Registry System: 1,3,5,2,4-Trioxadisilocino7,6-bpyrrole-7(6H)-carboxylic acid, 8-(cyanomethyl)tetrahydro-9-hydroxy-2,2,4,4-tetrakis(1-methylethyl)-, 1,1-dimethylethyl ester, (6aR,8S,9S,9aR)-(222854-81-1)

Safety Data

• Hazardous Substances Data: 222854-81-1(Hazardous Substances Data)

Usage

Siloxane ring

A ring structure containing silicon and oxygen atoms.

Pyrrole ring

A five-membered aromatic ring containing four carbon atoms and one nitrogen atom.

Carboxylic acid group

A functional group with the formula -COOH, consisting of a carbonyl group (C=O) and a hydroxyl group (-OH) bonded to the same carbon atom.

Cyanomethyl group

A functional group with the formula -CH2CN, consisting of a methylene group (-CH2-) bonded to a nitrile group (-CN).

Tetrahydro-9-hydroxy group

A four-carbon chain with a hydroxyl group (-OH) attached to the ninth carbon atom.

2,2,4,4-Tetrakis(1-methylethyl)

A tetrasubstituted carbon atom with four 1-methylethyl (tert-butyl) groups attached.

1,1-Dimethylethyl ester

An ester functional group derived from the reaction of a carboxylic acid with 1,1-dimethylethyl alcohol (tert-butyl alcohol).

(6aR,8S,9S,9aR)-

The stereochemistry of the compound, indicating the configuration of the chiral centers at the specified positions in the molecule.
The compound's highly specific and specialized structure suggests potential use in various pharmaceutical, industrial, or research applications.

Upstream product

• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 
• 222631-23-4 N-tert-butoxycarbonyl-2,3,6-trideoxy-3,6-imino-D-allo-heptononitrile 
• 24424-99-5 di-tert-butyl dicarbonate 
• 153172-31-7 (3aR,4R,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole 
• 153172-33-9 (3aR,4R,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-4,6a-dihydro-3aH-[1,3]dioxolo[4,5-c]pyrrole 
• 222631-08-5 2-((3aS,4S,6R,6aR)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo [4,5-c]pyrrol-4-yl)acetonitrile 
• 222631-20-1 2,3,6-trideoxy-3,6-imino-D-allo-heptononitrile 

Downstream Products

• 222854-88-8 2-[4-(3-benzoyl-2-methyl-isothioureido)-5-ethoxycarbonyl-1H-pyrrol-3-yl]-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-aza-5,7-disila-cyclopentacyclooctene-1-carboxylic acid tert-butyl ester 
• 222854-86-6 (1R)-1-[3-amino-1-N-benzyloxycarbonyl-2-ethoxycarbonylpyrrol-4-yl]-N-tert-butoxycarbonyl-1,2,4-trideoxy-1,4-imino-3,5-O-(1,1,3,3-tetraisopropyldisiloxa-1,3-diyl)-D-erythro-pentitol 
• 222854-89-9 2-(2-amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-aza-5,7-disila-cyclopentacyclooctene-1-carboxylic acid tert-butyl ester 
• 222854-87-7 (1R)-N-tert-butoxycarbonyl-1,2,4-trideoxy-1-(9-deazahypoxanthin-9-yl)-1,4-imino-3,5-O-(1,1,3,3-tetraisopropyldisiloxa-1,3-diyl)-D-erythro-pentitol 
• 222854-85-5 (2R,3aS,9aR)-2-[(Z)-1-Cyano-2-(ethoxycarbonylmethyl-amino)-vinyl]-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-aza-5,7-disila-cyclopentacyclooctene-1-carboxylic acid tert-butyl ester 
• 284490-18-2 (2R,3aS,9aR)-2-((Z)-1-Cyano-2-hydroxy-vinyl)-5,5,7,7-tetraisopropyl-tetrahydro-4,6,8-trioxa-1-aza-5,7-disila-cyclopentacyclooctene-1-carboxylic acid tert-butyl ester 
• 222854-83-3 N-tert-butoxycarbonyl-2,3,4,6-tetradeoxy-3,6-imino-5,7-O-(1,1,3,3-tetraisopropyldisiloxa-1,3-diyl)-D-ribo-heptononitrile 
• 222854-82-2 N-tert-butoxycarbonyl-2,3,6-trideoxy-4-O-[imidazole-(thiocarbonyl)]-3,6-imino-5,7-O-(1,1,3,3-tetraisopropyldisiloxa-1,3-diyl)-D-allo-heptononitrile 

Relevant articles and documents

Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases

Syntheses of the 'Immucillins', potent aza-C-nucleoside inhibitors of purine nucleoside phosphorylase are reported as well as those of 5-deoxy-, 5- deoxyfluoro- and 2-deoxy- analogues and others having modified bases. (C) 2000 Elsevier Science Ltd.