2229-36-9

Upstream product

• 2055-56-3 2-nitro-2'-aminodiphenylamine 
• 1516-58-1 o-azidonitrobenzene 
• 1464795-34-3 C₁₃H₈N₄O₄ 
• 118-92-3 anthranilic acid 
• 95-14-7 1,2,3-Benzotriazole 
• 88-73-3 2-Chloronitrobenzene 

Downstream Products

• 2055-57-4 2-(1H-benzo-1,2,3-triazole-1-yl)aniline 
• 61601-54-5 1-hydroxycarbazole 
• 86-74-8 9H-carbazole 
• 10560-89-1 2-(2-nitrophenyl)benzotriazole 
• 31438-22-9 1-nitro-9H-carbazole 

Relevant academic research and scientific papers

Amide compound containing 1-phenyl-1,2,3-triazole structure and application thereof

The invention discloses an amide compound containing 1-phenyl-1,2,3-triazole and application thereof. The amide compound containing 1-phenyl-1,2,3-triazole is characterized by having a formula shown in the attached figure, wherein R1 is selected from the

Photochemical C–H Activation: Generation of Indole and Carbazole Libraries, and First Total Synthesis of Clausenawalline D

The photolysis of N-aryltriazoles and N-arylbenzotriazoles leads to indoles and carbazoles, respectively. Because libraries of triazoles can be accessed rapidly, for example by the copper-catalyzed [3+2] cycloaddition reaction between alkynes and azides, this reaction allows the preparation of indoles in a single operation, by the simultaneous photolysis of the precursor library. As an example of such a synthesis of carbazoles, we prepared for the first time clausenawalline D, an antimalarial alkaloid that was recently isolated.

Organocatalytic triazole formation, followed by oxidative aromatization: Regioselective metal-free synthesis of benzotriazoles

Herein we report on our studies on the sequential one-pot combinations of amine-catalyzed multicomponent reactions (MCRs). We have developed the copper-free synthesis of functionalized bicyclic N-aryl-1,2,3-triazole and N-arylbenzotriazole products 4 and 5 from the simple unmodified starting materials through [3+2]-cycloaddition ([3+2]-CA) and oxidative aromatization reactions in one pot under amine catalysis. The sequential one-pot reaction proceeds in good yields with high selectivity by using pyrrolidine as the catalyst from the simple unmodified substrates of enones, aryl azides, and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). Furthermore, we have demonstrated the medicinal applications of products 4 and 5 through simple organic reactions. Organo-click approach to benzotriazoles: A practical synthesis of N-arylbenzotriazoles was achieved through the sequential one-pot combination of [3+2]-cycloaddition followed by 2,3-dichloro-5,6-dicyano-1,4- benzoquinone (DDQ)-mediated oxidative aromatization of unmodified cyclic enones with aryl azides. For the first time, the synthesis of privileged CF3 containing N-arylbenzotriazoles through metal-free catalysis has been discovered (see scheme). Copyright

Some structural changes on triazolyl-benzotriazoles and triazolyl-benzimidazolones as potential potassium channel activators. III

This paper reports the synthesis and pharmacological evaluation of some compounds, obtained by structural modifications of 1,2,3-triazolyl-benzotriazoles and 1,2,3-triazolyl-benzimidazolones, which had shown activity as potential activators of the big-con