2230-70-8

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 86, p. 3068, 1964 DOI: 10.1021/ja01069a019

InChI:InChI=1/C9H16O/c1-7-6-9(2,3)5-4-8(7)10/h7H,4-6H2,1-3H3

Upstream product

• 13395-71-6 2,4,4-trimethyl-2-cyclohexenone 
• 90676-26-9 2,4,4-Trimethyl-cyclohexanol 
• 134736-79-1 (+/-)-2,4,4-Trimethyl-2-cyclohexenyl acetate 
• 13395-73-8 4,4,6-trimethylcyclohex-2-en-1-one 
• 814-78-8 3-Methyl-3-buten-2-one 
• 4255-62-3 4,4-dimethylcyclohexane-1-one 
• 74-88-4 methyl iodide 
• 63184-86-1 2,6,6-trimethylcyclohexane-1,3-dione 
• 91212-95-2 4-Acetoxy-1,1,3-trimethyl-cyclohexan 
• 503-46-8 1,5,5-trimethylcyclohexene 
• 78-59-1 3,5,5-Trimethylcyclohex-2-en-1-one 
• 201230-82-2 carbon monoxide 
• 38441-63-3 2,4,4-Trimethyl-2,5-cyclohexadien-1-on 
• 64-18-6 formic acid 

Downstream Products

• 471-04-5 4,4-dimethyl-6-oxo-heptanoic acid 
• 122228-60-8 lavanducyanin 3 
• 103985-40-6 (2,4,4-trimethyl-1-cyclohexen-1-yl)methanol 
• 33858-67-2 C₁₇H₂₈N₃O₂P 

Relevant academic research and scientific papers

Total Syntheses of Pyocyanin, Lavanducyanin, and Marinocyanins A and B

Total syntheses of pyocyanin, lavanducyanin, and marinocyanins A and B have been accomplished. The N-substituted phenazin-1-one skeleton, a common framework of these natural products, was constructed through the oxidative condensation of pyrogallol with N-substituted benzene-1,2-diamine under an oxygen atmosphere in a single step. Regioselective bromination with N-bromosuccinimide at the C-2 position of N-alkylated phenazin-1-ones afforded brominated natural products.

TETRAHYDRONAPHTHALENE DERIVATIVES USEFUL AS NRF2 ACTIVATORS

Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use as Nrf2 activators and for their production.

Use of cyclic ketones in perfumery

PCT No. PCT/IB97/01092 Sec. 371 Date May 13, 1998 Sec. 102(e) Date May 13, 1998 PCT Filed Sep. 12, 1997 PCT Pub. No. WO98/13447 PCT Pub. Date Apr. 2, 1998The compounds of formula in which R stands for a methyl or ethyl group, are used as perfume ingredien

Halides-based electrophiles mediated epoxide ring-opening reactions of α,β-epoxysulfoxides in C6-series : Deoxygenation versus dehydration and an overall 1,2-keto transposition

New syntheses of α-thiosubstituted carbonyl compounds with the carbonyl carbon being the one that originally does not carry the sulfoxide group from six-membered ring α,β-epoxysulfoxides and several halides-based electrophiles are described. Mechanistic considerations for deoxygenation as well as dehydration reactions are also discussed. In addition, methodology for achieving 1,2-carbonyl transposition starting with isomerically pure cyclohexenyl sulfides derived from isophorone and cholestan-3-one is briefly reported.

Hydrocarbonylating Cyclization of Dienes, 5. - Model Experiments for the Synthesis of the Acorane Skeleton from Substituted 1,4-Dienes

Heading towards the generation of the five-membered ring substitution pattern in the acorane skeleton (1) the hydrocarbonylating cyclization of various substituted 1,4-dienes 3 to cyclopentanones 4 and 5 was studied.While octacarbonyldicobalt as catalyst precurser nearly exclusively leads to linking of the less substituted carbon centers, the more active (cyclooctadiene)rhodium complex also effects the formation of new quaternary centers.The 1,5-dienes 15a-e converted under the same conditions revealed no tendency to isomerize to 1,4-dienes with the same carbon skeleton or to form analogous cyclization products.Finally, using the model substrate 3i the regio- and stereoselective synthesis of the cyclopentanone system 4i containing the same substitution pattern as the five-membered ring of the target molecule 1 can be accomplished. - Keywords: Carbonylation of 1,4-dienes / Catalysis, cobalt / Catalysis, rhodium / Cyclopentanone derivatives