223103-04-6

Basic information

• Product Name: (4S,5R,6S)-3-((E)-3-Hydroxy-propenyl)-4-methyl-7-oxo-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester
• Synonyms: (4S,5R,6S)-3-((E)-3-Hydroxy-propenyl)-4-methyl-7-oxo-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester
• CAS NO: 223103-04-6
• Molecular Weight: 516.667
• Mol File: 223103-04-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S,5R,6S)-3-((E)-3-Hydroxy-propenyl)-4-methyl-7-oxo-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R,6S)-3-((E)-3-Hydroxy-propenyl)-4-methyl-7-oxo-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(223103-04-6)
• EPA Substance Registry System: (4S,5R,6S)-3-((E)-3-Hydroxy-propenyl)-4-methyl-7-oxo-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester(223103-04-6)

Safety Data

• Hazardous Substances Data: 223103-04-6(Hazardous Substances Data)

Upstream product

• 165817-82-3 4-nitrobenzyl (1R,5R,6S)-1-methyl-6-[(1R)-triethylsilanyloxy-ethyl]-2-(trifluoro-methanesulfonyloxy)-carbapen-2-em-3-carboxylate 
• 74141-13-2 1-tributylstannyl-3-hydroxypropene 

Downstream Products

• 243981-05-7 (4S,5R,6S)-3-Formyl-4-methyl-7-oxo-6-((R)-1-triethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 

Relevant articles and documents

The syntheses of functionalized 2-alkenyl and alkynyl-1-β- methyl-carbapenems via the Stille cross-coupling reaction

The Stille cross-coupling reaction is an extremely mild and versatile method for the coupling of organostannanes with vinyl triflates. This methodology has been extended to include functionalized 2-alkenyl and alkynyl-1-β-methylcarbapenems.