223123-49-7

Basic information

• Product Name: 1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylic acid
• Synonyms: 1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylic acid
• CAS NO: 223123-49-7
• Molecular Weight: 269.26
• Mol File: 223123-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylic acid(223123-49-7)
• EPA Substance Registry System: 1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylic acid(223123-49-7)

Safety Data

• Hazardous Substances Data: 223123-49-7(Hazardous Substances Data)

Upstream product

• 223123-04-4 ethyl 1-ethyl-4-hydroxy-2-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylate 
• 223122-99-4 ethyl 4-hydroxy-1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 61982-14-7 1-methyl-4-nitroimidazolyl-5-carboxylic acid chloroanhydride 
• 223123-99-7 1-ethyl-4-hydroxy-2-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylic acid 
• 223123-27-1 ethyl 1-methyl-5-phenyl-7-oxo-4,7-dihydro-1H-imidazo<4,5-b>pyridine-6-carboxylate 

Relevant articles and documents

A new synthesis of substituted imidazo[4,5-￡]pyridinones by reductive cyclisation of 4-nitro-l//-imidazol-5-yl di-, and tri-carbonyl compounds

A new synthetic route to the biologically important imidazo[4,5-6]pyridine ring system is described. An efficient method for the condensation of 4-nitro-l//-imidazole-5-carbonyl chlorides with activated methylene compounds using magnesium ethoxide has been developed. The imidazolyl di-, and tri-carbonyl compounds formed in this process were found to be good substrates for reductive cyclisation to the little studied 4-hydroxyimidazo[4,5-i]pyridinones by either catalytic hydrogenation over palladium or by treatment with alkaline sodium borohydride in the presence of palladium. Highly oxygenated derivatives of 1-deazapurines are thus readily available by this method.