223136-13-8Relevant academic research and scientific papers
One-pot three-component synthesis of α-amino nitriles catalyzed by 2,4,6-trichloro-1,3,5-triazine (cyanuric acid)
Das, Biswanath,Kumar, Rathod Aravind,Thirupathi, Ponnaboina
, p. 1206 - 1210 (2007)
A simple and efficient method has been developed for the synthesis of α-amino nitriles from aldehydes, amines and trimethylsilyl cyanide (Me3SiCN) in the presence of a catalytic amount of cyanuric acid at room temperature.
Synthesis and characterization of an acidic nanostructure based on magnetic polyvinyl alcohol as an efficient heterogeneous nanocatalyst for the synthesis of α-aminonitriles
Maleki, Ali,Rahimi, Jamal,Hajizadeh, Zoleikha,Niksefat, Maryam
, p. 58 - 65 (2018/12/13)
The present study described design, preparation and characterization of a new magnetic nanocomposite based on polyvinyl alcohol (PVA) as a non-toxic, water-soluble, high mechanical stable and low-cost polymer. Fourier transform infrared (FT-IR) spectroscopy, field-emission scanning electron microscopy (FE-SEM) image, transmission electron microscope (TEM) image, X-ray diffraction (XRD) pattern, energy-dispersive X-ray (EDX) analysis and thermogravimetric (TG) analysis were used to describe the morphological, chemical and physical properties of the prepared nanocatalyst. All these results confirmed the successful synthesis of Fe3O4@PVA-SO3H. This heterogeneous nanocatalyst was then successfully used for the synthesis of α-aminonitrile derivatives by starting from an aldehyde, an aniline and trimethylsilyl cyanide (TMSCN). High efficiency, green chemistry properties, simple and easy separation are the specific properties of this nanocomposite. Fe3O4@PVA-SO3H can be derived out by an external magnet and reused ten times without any changes in its structure.
Gallic acid grafted to amine-functionalized magnetic nanoparticles as a proficient catalyst for environmentally friendly synthesis of α-aminonitriles
Maleki, Ali,Azadegan, Sepide,Rahimi, Jamal
, (2019/03/26)
An effective approach of one-pot catalytic Strecker reaction between aromatic aldehydes, aniline or toluidine and trimethylsilyl cyanide in the presence of amine-functionalized Fe3O4@SiO2 nanoparticles grafted with gallic
Zn(OAc)2·2H2O-catalyzed one-pot efficient synthesis of α-amino nitriles
Reddy, V. Venkata Rami,Saritha,Ramu,Varala, Ravi,Jayashree
, p. 7439 - 7442 (2015/04/22)
A mild, efficient one-pot three component strecker reaction involving electronically and structurally divergent aldehydes, amines and trimethly silyl cyanide in chloroform as solvent at room temperature was accomplished in moderate to excellent yields using an inexpensive and readily available catalyst, Zn(OAc)2.2H2O.
Chitosan: A highly efficient renewable and recoverable bio-polymer catalyst for the expeditious synthesis of α-amino nitriles and imines under mild conditions
Dekamin, Mohammad G.,Azimoshan, Mojtaba,Ramezani, Leila
supporting information, p. 811 - 820 (2013/04/10)
Commercial chitosan-without any post-modification with active Bronsted or Lewis acid centers-was found to be a highly efficient renewable and recoverable bio-polymer catalyst for the rapid and convenient synthesis of α-amino nitriles or imines from aromatic aldehydes and amines under mild reaction conditions at room temperature in high to quantitative yields. The α-amino nitrile derivatives were prepared through the Strecker reaction using trimethylsilyl cyanide (TMSCN) and catalyzed by chitosan as a heterogeneous bifunctional organocatalyst.
Ga-TUD-1: A new heterogeneous mesoporous catalyst for the solventless expeditious synthesis of α-aminonitriles
Karmakar, Bikash,Sinhamahapatra, Apurba,Panda, Asit Baran,Banerji, Julie,Chowdhury, Biswajit
scheme or table, p. 111 - 117 (2011/10/13)
The high surface area three-dimensional porous catalyst has been prepared and characterized by TEM, BET S.A, low angle XRD, 29Si MAS NMR, NH3 TPD techniques. A simple, efficient and rapid method for the green synthesis of α-aminonitriles has been demonstrated over a new mesoporous gallosilicate catalyst Ga-TUD-1. The solventless technique has been applied for the synthesis of a range of compounds with variable functionality with excellent yield and selectivity. The catalyst has been recycled four times with reproducible yield.
K2PdCl4 catalyzed efficient multicomponent synthesis of α-aminonitriles in aqueous media
Karmakar, Bikash,Banerji, Julie
scheme or table, p. 2748 - 2750 (2010/07/06)
An efficient, mild and environmentally friendly method has been developed for the Strecker reaction to synthesize α-aminonitriles in the presence of K2PdCl4 as a catalyst. The three-component one-pot condensation of an aldehyde, amine and trimethylsilyl cyanide proceeded smoothly in water to afford the corresponding product in high yield with short reaction times. Crown Copyright
