2232-12-4

Usage

Uses

Used in Pharmaceutical Industry:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent for the preparation of nitriles from corresponding alcohols and amines via oxidative conversion. This application is essential in the synthesis of various pharmaceutical compounds, making it a valuable component in drug development.
Used in Chemical Synthesis:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent for the chemoselective, stereospecific iododesilylation of silylated alkenes. This process is crucial in the synthesis of complex organic molecules, which are vital in various chemical and pharmaceutical applications.
Used in Organic Chemistry:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent for the preparation of N-benzyl toluenesulfonamides via sulfonylamidation of alkylbenzenes with toluenesulfonamide in the presence of diiododimethylhydantoin. This application is significant in the synthesis of various organic compounds, contributing to the advancement of organic chemistry.
Used in Iodination Reactions:
1,3-DIIODO-5,5-DIMETHYLHYDANTOIN is used as a reagent in iodination reactions, which are essential in the synthesis of various chemical compounds and materials. Its efficiency and cost-effectiveness make it a preferred choice for iodination processes in different industries, including pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C5H6I2N2O2/c1-5(2)3(10)8(6)4(11)9(5)7/h1-2H3

Upstream product

• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 

Downstream Products

• 104296-15-3 1-iodo-2-methoxynaphthalene 
• 7553-56-2 iodine 
• 50668-21-8 3-iodo-9-ethylcarbazole 
• 1324392-91-7 (Al(N₄C₁₉H₄I₄(C₆F₅)3)(NC₅H₅)2) 

Relevant academic research and scientific papers

Preparation method of 2-bromo-5-iodobenzyl alcohol

The invention discloses a preparation method of 2-bromo-5-iodobenzyl alcohol. A synthesis route is simple and typical, and is simple and convenient to operate, the yield of target products is high, 1,3-diiodo-5,5-dimethyl hydantoin as an iodization reagen

1, 3-arylhydantoins Diiodothyronine manufacturing method

PROBLEM TO BE SOLVED: To provide a method for producing 1,3-diiodohydantoins easily and economically. SOLUTION: In the method for producing 1,3-diiodohydantoins represented by formula, hydantoins such as 5,5-dimethylhydantoin, hypochlorite or a hypochlorite aqueous solution, and at least one of iodine, an iodine ion source and an acid are reacted in at least one of an aqueous solvent and an organic solvent. In the formula, R1and R2may be the same or different mutually and are each a hydrogen atom or a 1-6C alkyl group. In this method, iodine monochloride is not required, and consequently, 1,3-diiodohydantoin can be produced easily and economically. COPYRIGHT: (C)2013,JPOandINPIT

PRODUCTION METHOD FOR HALOHYDRANTOIN COMPOUND AND HALOHYDRANTOIN COMPOUND

A method for producing a halohydantoin compound according to the present invention includes the steps of: (a) providing, in a dryer, a composition containing (i) at least one component selected from the group consisting of water, an organic solvent, and elemental halogen and (ii) a halohydantoin compound; and (b) drying the composition under reduced pressure in the dryer, the reduced pressure being reduced to a pressure lower than atmospheric pressure while introducing an inert gas from an outside source into the dryer.

METHOD FOR PRODUCING HALOHYDANTOIN COMPOUND

A production method of the present invention is a method for producing a halohydantoin compound in which method a composition including a halohydantoin compound and an impurity is treated, the method including the step of adding the composition to a mixed solvent of water and an organic solvent and washing the composition.

Carbon-14 labeling of a trifluoromethoxy group: Synthesis of a substance P antagonist

Synthesis of a carbon-14 labeled trifluoromethoxy group has been accomplished using the stepwise oxidative fluorination-desulfurization of a readily prepared [14C]xanthate (5). This novel labeling procedure allowed a rapid synthesis of substanc