223251-13-6 Usage
Description
[4-[2-(1-piperidinyl)ethoxy]phenyl]methanol, also known as 4-[2-(1-Piperidinyl)ethoxy]-benzenemethanol, is an organic compound that serves as a crucial intermediate in the pharmaceutical industry. It is characterized by its unique molecular structure, which includes a phenyl group connected to a methanol group through an ethoxy linkage, with a piperidinyl group attached to the ethoxy chain. [4-[2-(1-piperidinyl)ethoxy]phenyl]methanol is known for its potential applications in the development of therapeutic agents, particularly in the treatment of cancer.
Uses
Used in Pharmaceutical Industry:
[4-[2-(1-piperidinyl)ethoxy]phenyl]methanol is used as an intermediate in the synthesis of Pipendoxifene (P479850), a 2-Ph indole selective estrogen receptor modulator (SERM). This SERM has demonstrated an excellent preclinical pharmacological profile and has been selected for further development as a treatment for metastatic breast cancer. The compound's unique structure allows it to modulate estrogen receptor activity, which can help in the treatment and management of hormone receptor-positive breast cancer.
Used in Cancer Treatment:
In the field of oncology, [4-[2-(1-piperidinyl)ethoxy]phenyl]methanol plays a significant role in the development of Pipendoxifene, a potential treatment for metastatic breast cancer. This SERM works by selectively binding to estrogen receptors, which can help in inhibiting the growth and progression of cancer cells that rely on estrogen for their survival and proliferation. The development of Pipendoxifene as a therapeutic agent highlights the importance of [4-[2-(1-piperidinyl)ethoxy]phenyl]methanol in advancing cancer treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 223251-13-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,2,5 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 223251-13:
(8*2)+(7*2)+(6*3)+(5*2)+(4*5)+(3*1)+(2*1)+(1*3)=86
86 % 10 = 6
So 223251-13-6 is a valid CAS Registry Number.
223251-13-6Relevant articles and documents
Naphthyl urea compound, and preparation method and application thereof
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, (2021/06/21)
The invention provides a naphthyl urea compound, and a preparation method and application thereof. A naphthyl urea parent nucleus group with biological activity contained in the naphthyl urea compound is further chemically modified to generate a plurality of compounds with higher biological activity, so that the wide application of the compounds in biological medicines and the development prospect of pharmaceutical preparations are expanded. The compound can obviously inhibit proliferation of cells of liver cancer, breast cancer, lung cancer, drug-resistant lung cancer, leukemia and the like at low dosage (submicromole), induce arrest of a cell cycle G2/M phase and promote cell apoptosis, so that the compound has a prospect of being developed into an anti-tumor drug.
Compound and preparation method and application thereof
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Paragraph 0083-0088; 0131-0136; 0179-0184; 0227-0232; 0275, (2020/12/15)
The invention relates to the field of medicinal chemistry and pharmacotherapeutics, in particular to a bazedoxifene analog compound and a preparation method thereof, application of the bazedoxifene analog compound in a GP130 small molecule inhibitor and t
Process for the preparation of intermediates palestinian multi-past fragrance acetate
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, (2018/02/04)
The invention discloses a preparation method of bazedoxifene acetate intermediate. The present invention provides a preparation method of bazedoxifene acetate intermediate compound 3, and the preparation method comprises the following steps: step 1, in a
