223270-77-7

Basic information

• Product Name: 2-[3-(tert-butoxycarbonyl-methyl-amino)-propionyloxy]-4-methyl-pentanoic acid benzhydryl ester
• Synonyms: 2-[3-(tert-butoxycarbonyl-methyl-amino)-propionyloxy]-4-methyl-pentanoic acid benzhydryl ester
• CAS NO: 223270-77-7
• Molecular Weight: 483.605
• Mol File: 223270-77-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[3-(tert-butoxycarbonyl-methyl-amino)-propionyloxy]-4-methyl-pentanoic acid benzhydryl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(tert-butoxycarbonyl-methyl-amino)-propionyloxy]-4-methyl-pentanoic acid benzhydryl ester(223270-77-7)
• EPA Substance Registry System: 2-[3-(tert-butoxycarbonyl-methyl-amino)-propionyloxy]-4-methyl-pentanoic acid benzhydryl ester(223270-77-7)

Safety Data

• Hazardous Substances Data: 223270-77-7(Hazardous Substances Data)

Upstream product

• 20312-37-2 (R)-2-hydroxy-4-methylpentanoic acid 
• 328-38-1 (R)-leucine 
• 124072-61-3 N-t-butoxycarbonyl-N-methyl-β-alanine 
• 168069-99-6 Diphenylmethyl (2R)-2-hydroxy-4-methylpentanoate 

Downstream Products

• 223270-83-5 (S)-2-{(R)-2-[3-(tert-Butoxycarbonyl-methyl-amino)-propionyloxy]-4-methyl-pentanoylamino}-4-methyl-pentanoic acid (S)-1-[((S)-1-benzyloxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-3-methyl-butyl ester 
• 223270-86-8 (S)-4-Methyl-2-[(R)-4-methyl-2-(3-methylamino-propionyloxy)-pentanoylamino]-pentanoic acid (S)-1-[((S)-1-benzyloxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-3-methyl-butyl ester 
• 223270-89-1 (S)-4-Methyl-2-[(R)-4-methyl-2-(3-methylamino-propionyloxy)-pentanoylamino]-pentanoic acid (S)-1-[((S)-1-carboxy-2-phenyl-ethyl)-methyl-carbamoyl]-3-methyl-butyl ester 

Relevant articles and documents

Synthesis and evaluation of backbone/amide-modified analogs of leualacin

Leualacin (1), a cyclic depsi-pentapeptide, and its backbone/amidemodified analogs 2-4 were synthesized. Amide analogue 3 exhibited stronger vasodilatory effects. It also strongly inhibited collagen- and arachidonic acid (AA)induced platelet aggregations with IC50s of 0.6 μM and 2.0 μM, respectively.