223379-82-6Relevant academic research and scientific papers
Efficient two-step synthesis of structurally diverse indolo[2,3-: B] quinoline derivatives
Kundal, Sandip,Chakraborty, Baitan,Paul, Kartick,Jana, Umasish
supporting information, p. 2321 - 2325 (2019/03/08)
A general and efficient synthesis of diverse tetracyclic indolo[2,3-b]quinoline derivatives was achieved through palladium-catalyzed domino carboannulation/cross-coupling and DDQ-mediated double cross-dehydrogenative C-N bond formation. This approach provides a straightforward, atom-economical and concise route to easily access a diverse range of tetracyclic indolo[2,3-b]quinolines and their analogues in excellent yields with good tolerance of functional groups.
Synthesis of Indolo-and Benzothieno[2,3-b]quinolines by a Cascade Cyclization of o-Alkynylisocyanobenzene Derivatives
Khaikate, Onnicha,Inthalaeng, Natthamon,Meesin, Jatuporn,Kantarod, Kritchasorn,Pohmakotr, Manat,Reutrakul, Vichai,Soorukram, Darunee,Leowanawat, Pawaret,Kuhakarn, Chutima
, (2019/11/29)
A new synthetic approach for the synthesis of indolo[2,3-b]quinolines and benzothieno[2,3-b]quinolines has been developed by employing the freshly prepared o-alkynylisocyanobenzenes derived from o-alkynylformamide derivatives as substrates. The synthetic transformations involved chloride-ion-triggered 6-endo cyclization of o-alkynylisocyanobenzenes to generate 2-chloroquinolines in situ, which further cyclized intramolecularly with nitrogen or sulfur atom via a cascade process to provide the corresponding indolo[2,3-b]quinolines and benzothieno[2,3-b]quinolines, respectively, in moderate to excellent yields.
Iminophoshorane-mediated synthesis of the alkaloid cryptotackieine
Molina,Fresneda,Delgado
, p. 326 - 329 (2007/10/03)
A new synthesis of the alkaloid cryptotackieine based on the stepwise formation of the pyridine and indole ring is described. The key step, formation of the appropriate 3-arylquinoline, involves a Staudinger/aza- Wittig/electrocyclic ring-closure process.
