223383-63-9

Basic information

• Product Name: bis(4,5-dihydro-2-oxazolylmethyl)phenylphosphine
• CAS NO: 223383-63-9
• Molecular Weight: 276.275
• Mol File: 223383-63-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bis(4,5-dihydro-2-oxazolylmethyl)phenylphosphine(CAS DataBase Reference)
• NIST Chemistry Reference: bis(4,5-dihydro-2-oxazolylmethyl)phenylphosphine(223383-63-9)
• EPA Substance Registry System: bis(4,5-dihydro-2-oxazolylmethyl)phenylphosphine(223383-63-9)

Safety Data

• Hazardous Substances Data: 223383-63-9(Hazardous Substances Data)

Upstream product

• 1120-64-5 2-methyl-4,5-dihydro-1,3-oxazole 
• 1079-66-9 chloro-diphenylphosphine 

Downstream Products

• 1201649-34-4 [PdCl₂(bis(4,5-dihydro-2-oxazolylmethyl)phenylphosphine-N,P)] 
• 1038986-81-0 [Ni(bis(4,5-dihydro-2-oxazolylmethyl)phenylphosphine)Cl₂] 
• 223383-68-4 RuCl(C₆H₆)(C₁₄H₁₇N₂O₂P)⁽¹⁺⁾*CF₃SO₃^(1-) = [RuCl(C₆H₆)(C₁₄H₁₇N₂O₂P)](CF₃SO₃) 

Relevant articles and documents

Catalytic transfer hydrogenation of ketones by the use of ruthenium complexes incorporating the new tridentate ligand, bis(2-oxazolin-2-ylmethyl)phenylphosphine

The new heterofunctional phosphine ligand bis(2-oxazolin-2-ylmethyl)phenylphosphine (N,P,N) has been prepared and has allowed the synthesis of the ruthenium complexes fac-[RuCl2(DMSO)(N,P,N)] 1, fac-[RuCl2(PPh3)(N,P,N)] 2, [RuCl(η6-C6H6)(N,P,N)][O 3SCF3] 3 and [Ru(η6-C6H6)(N,P,N)][O3SCF 3]2 4. When tridentate, as in 1, 2, and 4, this ligand co-ordinates in a facial-type mode. In complex 3, it acts as a P,N-chelate with a dangling oxazoline ring. The structures of the ligand, 2·CH2Cl2·0.25C6H14 and 3 have been determined by X-ray diffraction. Complexes 1-4 catalyse the transfer hydrogenation reaction between propan-2-ol and ketones. Only small differences in reactivity were observed between 3 and 4, despite the different ligand bonding mode in these complexes. For the best catalyst, 2, yields up to 97% were obtained and turnover frequencies may be as high as 112 000 h-1.