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2-Methyl-5-(tributylstannyl)thiazole is a chemical compound characterized by a molecular formula C13H25NSnS. It is a thiazole derivative featuring a tributylstannyl group attached to the fifth position of the thiazole ring. 2-Methyl-5-(tributylstannyl)thiazole is recognized for its versatility in organic synthesis and its potential as a building block for the creation of more complex organic molecules. The tributylstannyl group's reactivity allows for facile substitution with other functional groups, rendering it an invaluable asset in the preparation of a diverse array of organic compounds. Furthermore, 2-Methyl-5-(tributylstannyl)thiazole has garnered interest due to its potential biological activities, particularly its antimicrobial properties, which are currently under investigation.

223418-75-5

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223418-75-5 Usage

Uses

Used in Organic Synthesis:
2-Methyl-5-(tributylstannyl)thiazole is utilized as a key intermediate in organic synthesis for the preparation of a variety of complex organic molecules. Its tributylstannyl group facilitates easy replacement with other functional groups, making it a versatile component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Antimicrobial Applications:
2-Methyl-5-(tributylstannyl)thiazole is studied for its potential use as an antimicrobial agent. Its unique structure and properties are being investigated for their ability to combat various types of microorganisms, which could be beneficial in the development of new antimicrobial drugs and treatments.
Used in Chemical Research:
In the field of chemical research, 2-Methyl-5-(tributylstannyl)thiazole serves as a model compound for studying the reactivity and properties of organotin compounds. Its use in research contributes to a deeper understanding of the mechanisms and applications of organotin chemistry, which can lead to the discovery of new synthetic methods and applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 223418-75-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,4,1 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 223418-75:
(8*2)+(7*2)+(6*3)+(5*4)+(4*1)+(3*8)+(2*7)+(1*5)=115
115 % 10 = 5
So 223418-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H4NS.2C4H9.C3H7.Sn/c1-4-5-2-3-6-4;2*1-3-4-2;1-3-2;/h2H,1H3;2*1,3-4H2,2H3;1,3H2,2H3;/rC15H29NSSn/c1-5-8-11-18(10-7-3,12-9-6-2)15-13-16-14(4)17-15/h13H,5-12H2,1-4H3

223418-75-5 Well-known Company Product Price

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  • Aldrich

  • (SYX00105)  2-Methyl-5-(tributylstannyl)thiazole  AldrichCPR

  • 223418-75-5

  • SYX00105-1G

  • 9,026.55CNY

  • Detail

223418-75-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methyl-5-(tributylstannyl)thiazole

1.2 Other means of identification

Product number -
Other names 2-Methyl-5-tosyloxymethyl-4,5,6,7-tetrahydrobenzo[d]thiazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:223418-75-5 SDS

223418-75-5Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS

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Paragraph 0552; 0553; 0554, (2019/02/05)

Aminopyrazine compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.

INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF

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, (2019/09/30)

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

1,2,4-TRIAZOL-5-ONES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITIES

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Paragraph 0392, (2014/09/29)

Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-lR), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.

IMIDAZOLIDINONES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITIES

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Paragraph 0378, (2014/10/29)

Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.

8-ETHYL-6-(ARYL)PYRIDO [2,3-D]PYRIMIDIN-7(8H) -ONES FOR THE TREATMENT OF NERVOUS SYSTEM DISORDERS AND CANCER

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Paragraph 00636, (2013/04/10)

Provided herein are PAK inhibitors and methods of utilizing PAK inhibitors for the treatment of CNS disorders such as neuropsychiatric disorders or neurofibromatosis. Also described herein are methods of utilizing PAK inhibitors for the treatment of cancer.

FUSED HETEROAROMATIC PYRROLIDINONES

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Page/Page column 119, (2011/07/06)

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, L1, L2, R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.

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