223419-91-8Relevant academic research and scientific papers
An Efficient Multigram Synthesis of the Potent Histamine H3 Antagonist GT-2331 and the Reassessment of the Absolute Configuration
Liu, Huaqing,Kerdesky, Francis A.,Black, Lawrence A.,Fitzgerald, Michael,Henry, Rodger,Esbenshade, Timothy A.,Hancock, Arthur A.,Bennani, Youssef L.
, p. 192 - 194 (2007/10/03)
GT-2331 is a potent histamine H3 antagonist which has entered clinical trials. Efficient multigram syntheses of this compound and its enantiomer are described. The literature reports that GT-2331 is the dextrorotatory (+), more potent, enantiom
