223446-86-4Relevant academic research and scientific papers
A zinc - Aldimine complex
Müller,Vahrenkamp
, p. 181 - 185 (2008/10/08)
Dimethylaminobenzaldimine - zinc-bis(pentafluorothiophenolate) was obtained from the reaction of dimethylaminobenzaldehyde with ammonia-contaminated zinc-bis(pentafluorothiophenolate) and characterized by a structure determination. Zinc effects the cataly
Alcohol and aldehyde adducts of zinc thiolates: Structural modeling of alcoholdehydrogenase
Mueller, Bodo,Schneider, Astrid,Tesmer, Markus,Vahrenkamp, Heinrich
, p. 1900 - 1907 (2008/10/08)
Bis(pentafluorothiophenolato)zinc (1) and bis(2,4,6-triisopropylthiophenolato)zinc (2) can be combined with nitrogen-containing derivatives of benzyl alcohol and benzaldehyde to form (N.O-chelate) zinc thiolates. 2-Pyridylmethanol as well as 2-quinolylmethanol (HetMeOH) yield [(HetMeO)Zn(SR)]4 (3, 4) having a cyclo-Zn4(μ-O)4 backbone and only terminal SR. Likewise, thiolate 1 and 2-(dimethylamino)benzyl alcohol form zwitterionic [(dimethylammoniobenzylato)Zn(SR)2]2 (5) with bridging alkoxide and terminal thiolate. In contrast, 6-picoIylmethanol (PicMeOH) and thiolate 1 result in [(PicMeOH)Zn(SC6F5)2] (6) containing zinc in a tetrahedral ZnNS2O, environment. Simple aromatic aldehydes form polymeric complexes [(RCHO)Zn(SC6F5)2] (7: R = p-tolyl, 8: R = mesityl) with a [Zn-S] backbone. Chelating aldehydes (CA) yield mononuclear complexes with tetrahedral ZnNS2O coordination (CA)Zn(SC6F5)2] (9, CA = pyridine-2-carbaldehyde; 10, CA = 6-methylpyridine-2-carbaldehyde; 11, CA = 6-methoxypyridine-2-carbaldehyde; 12, CA = quinoline-2carbaldehyde; 13, CA = 2-(dimethylamino)benzaldehyde). In contrast, N-methylimidazole-2-carbaldehyde (ImA) is coordinated twice in tetrahedral [(ImA)2Zn(SC6F5)2] (14) lacking any Zn-O interactions. Pyridine-2,6dicarbaldehyde (PDA) forms trigonal bipyramidal [(PDA)Zn(SC6F5)2] (15) with ZnNO2S2 ligation. The structures of 3, 4, 6, 8, 10, 11, 13, and 14 were determined crystallographically, and the structures of 5 and 15 were deduced from those of the corresponding ZnBr2 complexes. The ZnNS2O coordination pattern observed for the enzyme has been reproduced to a very good approximation. In complexes 6 and 10, which are almost superimposable, it is realized for both the corresponding alcohol and aldehyde.
