223463-19-2

Basic information

• Product Name: 1-Bromo-3-hexyloxymethyl-5-iodobenzene
• Synonyms: 1-Bromo-3-hexyloxymethyl-5-iodobenzene
• CAS NO: 223463-19-2
• Molecular Weight: 397.094
• Mol File: 223463-19-2.mol

Chemical Properties

• CAS DataBase Reference: 1-Bromo-3-hexyloxymethyl-5-iodobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-3-hexyloxymethyl-5-iodobenzene(223463-19-2)
• EPA Substance Registry System: 1-Bromo-3-hexyloxymethyl-5-iodobenzene(223463-19-2)

Safety Data

• Hazardous Substances Data: 223463-19-2(Hazardous Substances Data)

Upstream product

• 111-25-1 1-bromo-hexane 
• 188813-08-3 1-bromo-3-(hydroxymethyl)-5-iodobenzene 
• 188815-32-9 3-bromo-5-iodo-benzoic acid 
• 225932-12-7 1,3-Dibromo-5-hexyloxymethylbenzene 

Downstream Products

• 1360001-91-7 C₃₇H₄₄Br₂N₂O₂ 
• 1347067-81-5 C₄₀H₄₂O₂ 
• 1347067-79-1 C₄₆H₅₈O₂Si₂ 
• 1347067-77-9 C₃₅H₃₉Br₂NO₂ 
• 1347067-76-8 C₃₆H₄₀Br₂O₂ 
• 1347068-18-1 C₃₉H₃₉Br₂NO₂ 
• 223463-18-1 5,5''-bis<5-iodo-3-hexoxymethylphenyl>-2,2':6',2''-terpyridine 
• 296761-66-5 5,5-Bis[3-(3-hexyloxymethyl-5-triisopropylsilylethynylphenylethynyl)-5-(methoxymethoxymethyl)phenyl]-[2,2']bipyridinyl 
• 296761-67-6 5,5-Bis[3-(3-ethynyl-5-hexyloxymethylphenylethynyl)-5-(methoxymethoxymethyl)phenyl]-[2,2']bipyridinyl 
• 296761-59-6 1-Hexyloxymethyl-3-triisopropylsilylethynyl-5-trimethylsilylethynylbenzene 
• 296761-60-9 (2-(3-ethynyl-5-((hexyloxy)methyl)phenyl)ethynyl)triisopropylsilane 
• 314250-13-0 5,5''-bis[3-hexyloxymethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,2':6',2''-terpyridine 
• 314250-12-9 2-bromo-5-[3-hexyloxymethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine 
• 314250-11-8 1-hexyloxymethyl-3,5-diiodbenzene 

Relevant articles and documents

A shape-persistent macrocycle with two opposing 2,2':6',2'-Terpyridine units

The synthesis reported here of the shape-persistent macrocycle 9 with two opposing terpyridine units, and with pendant flexible chains for solubility reasons, was achieved by Suzuki cross-coupling of two 'half-cycles', the bisboronic acid ester 7 and its diiodo counterpart 8. Cycle 9 was obtained on a 100 mg scale in a yield of 20%. It was characterized by FAB mass spectrometry and 1H and 13C NMR spectroscopy. Cycle 9 is the first shape-persistent cycle containing terpyridine units that is larger than cyclosexipyridine. An improved synthesis of the important building block dibromoterpyridine 12 is also presented.

Synthesis of 5,5'-disubstituted 2,2'-bipyridines for modular chemistry

A 0.5-11 g scale synthesis of the 5,5'-disubstituted 2,2'-bipyridines 8 is described. The pyridine units are connected to one another by Pd-catalyzed cross-coupling reactions. This method allows one to introduce bromo functions and flexible chains at the