22353-38-4 Usage
General Description
3-CHLORO-2-HYDROXY-5-NITROPYRIDINE is a chemical compound with the molecular formula C5H3ClN2O3. It is a synthetic organic compound that contains a chloro group, a hydroxy group, and a nitro group attached to a pyridine ring. 3-CHLORO-2-HYDROXY-5-NITROPYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential as a molecular building block in organic chemistry. The presence of the nitro and chloro groups makes 3-CHLORO-2-HYDROXY-5-NITROPYRIDINE a reactive and versatile compound with various potential applications in the field of chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 22353-38-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,3,5 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 22353-38:
(7*2)+(6*2)+(5*3)+(4*5)+(3*3)+(2*3)+(1*8)=84
84 % 10 = 4
So 22353-38-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClNO/c1-4-2-5(7)6(9)8-3-4/h2-3H,1H3,(H,8,9)
22353-38-4Relevant articles and documents
Facile entry into structurally diverse, privileged, (hetero)arene-fused N-alkoxy 3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-ones
Sapegin, Alexander,Reutskaya, Elena,Smirnov, Alexey,Korsakov, Mikhail,Krasavin, Mikhail
supporting information, p. 5877 - 5880 (2016/12/14)
Rare and highly medicinally relevant N-alkoxy-substituted benzo[1,4]oxazepines have been synthesized conveniently via the base-promoted SNAr/Smiles rearrangement/SNAr tandem cyclization of N-alkoxysalicylamides with a range of bis-electrophilic substrates; subsequent de-alkylation gives rise to the respective N-hydroxy versions. The compounds reported herein significantly add to the contemporary arsenal of small molecule tools for drug discovery.
