22353-40-8Relevant articles and documents
PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS
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Page/Page column 55, (2015/01/16)
The description relates to a pyridyl compound of Formula 1 wherein A, B, X, R1, R2, R3, R4, R5, R6, and n are as defined in the specification, in all their isotopic forms, stereoisomeric and tautomeric forms and mixtures thereof in all ratios, their pharmaceutically acceptable salts, N-oxides, pharmaceutically acceptable solvates, isosteres and prodrugs thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia. The description also relates to a process for the manufacture of the pyridyl compound and a pharmaceutical composition containing the pyridyl compound.
Synthesis of N-(5-chloro-6-(quinolin-3-yloxy)pyridin-3-yl) benzenesulfonamide derivatives as non-TZD peroxisome proliferator-activated receptor γ (PPARγ) agonist
Bajare, Swapnil,Anthony, Jessy,Nair, Amrutha,Marita, Rosalind,Damre, Anagha,Patel, Dharmeshkumar,Rao, Chandrika,Sivaramakrishnan,Deka, Nabajyoti
, p. 355 - 360 (2013/02/21)
The thiazolidinediones (TZDs) are a class of oral antidiabetic drugs that improve insulin sensitivity in patients with type 2 diabetes. Although the mechanism by which the TZDs lower insulin resistance is unclear, they are known to target the peroxisome p
3-AMINO-PYRIDINE DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS
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Page/Page column 24, (2008/06/13)
The picsenl invention provides novel compounds represented by the general formula (I): wherein Ar is a quinoline or isoquinoline moiety which is substituted or unsubstituted; B is -O. -S-. or -NH-: R1 is hydrogen or S(O)2R4: R2 is S(O)2R4. C(O)OR5. or C(O