22354-77-4

Upstream product

• 636-99-7 4-nitrophenylhydrazine hydrochloride 
• 4231-68-9 3-hydroxy-1-phenyl-1,2,4-1H-triazole 
• 64-18-6 formic acid 
• 16246-34-7 4-nitrophenylsemicarbazide 

Downstream Products

• 42110-29-2 diethyl (1-p-nitrophenyl-1H-1,2,4-triazol-3-yl) phosphorothioate 
• 158895-51-3 1-(4-aminophenyl)-3-propoxy-1H-1,2,4-triazole 
• 158895-50-2 1-(4-aminophenyl)-3-ethoxy-1H-1,2,4-triazole 
• 158895-63-7 Acetic acid (2R,3R,4S,5R,6R)-3,5-diacetoxy-2-acetoxymethyl-6-{3-[4-(3-propoxy-[1,2,4]triazol-1-yl)-phenyl]-thioureido}-tetrahydro-pyran-4-yl ester 
• 158895-62-6 Acetic acid (2R,3R,4S,5R,6R)-3,5-diacetoxy-2-acetoxymethyl-6-{3-[4-(3-ethoxy-[1,2,4]triazol-1-yl)-phenyl]-thioureido}-tetrahydro-pyran-4-yl ester 
• 158895-53-5 4-(3-propoxy-1H-1,2,4-triazol-1-yl)phenyl isothiocyanate 
• 158895-52-4 4-(3-ethoxy-1H-1,2,4-triazol-1-yl)phenyl isothiocyanate 

Relevant academic research and scientific papers

Hapten of organophosphorus triazophos pesticide and preparation method thereof

The invention relates to the technical field of immunochemical analysis and pesticide residue detection, in particular to a hapten of an organophosphorus triazophos pesticide and a preparation method of the hapten. According to the preparation method, 1-phenyl-3-hydroxy-1, 2, 4-triazole serves as a raw material, and the hapten of the organophosphorus triazophos pesticide is synthesized through nitration reaction, substitution reaction, reduction reaction and carboxyl active group introduction reaction. Therefore, the antibody with high specificity and high affinity to organophosphorus pesticides can be prepared.

Synthesis and antifungal activity evaluation of new 1,2,4-triazole derivatives bearing salicylidene hydrazide moiety

A series of new N'-(arylidene)-2-[(1-(4-nitrophenyl)-1H-1,2,4-triazol-3-yl)oxy]acetohydrazide derivatives (1- 16) were prepared and tested for theira ntifungal activity against six plant pathogens, three human pathogens and two nonpathogen microorganisms. The target compounds were obtained with a multi-step reaction starting from 4- substitutedarylhydrazine derivatives and the structures of final compounds have been elucidated with IR, NMR, Mass spectroscopy data and elemental analysis results. The antifungal activity of the compounds was determined against eleven different Fusarium, Trichoderma, Aspergillus and Penicilliumspeciesby using microdilution method. Most of the target compounds showed excellent antifungal activity against a variety of fungal pathogens.

Synthesis and anti-myxovirus activity of some novel N,N'-disubstituted thioureas

A series of new N,N'-disubstituted thioureas were prepared and evaluated in vitro for their activity against myxoviruses. Compound N-[4-(3-propoxy-1H-1,2,4-triazol-1-yl)phenyl]-N'-(2-pyrazinyl)thiourea 5d exhibited specific activity against respiratory sy