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223564-75-8

223564-75-8

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223564-75-8 Usage

Type of compound

Benzene derivative

Functional groups

Bromine atom, 2-methylpropoxy (isopropyl) ether group

Usage

Building block for pharmaceuticals and organic compounds, research and development

Physical state

Colorless liquid

Odor

Slightly sweet

Solubility

Soluble in organic solvents (e.g., ethanol, acetone)

Safety precautions

Handle with caution, potential health hazards if inhaled or ingested, follow proper safety protocols

Check Digit Verification of cas no

The CAS Registry Mumber 223564-75-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,5,6 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 223564-75:
(8*2)+(7*2)+(6*3)+(5*5)+(4*6)+(3*4)+(2*7)+(1*5)=128
128 % 10 = 8
So 223564-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H13BrO/c1-8(2)7-12-10-5-3-4-9(11)6-10/h3-6,8H,7H2,1-2H3

223564-75-8Downstream Products

223564-75-8Relevant articles and documents

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4)inhibitors, compound profiling in cell-based target engagement assays

Le Bihan, Yann-Va?,Lanigan, Rachel M.,Atrash, Butrus,McLaughlin, Mark G.,Velupillai, Srikannathasan,Malcolm, Andrew G.,England, Katherine S.,Ruda, Gian Filippo,Mok, N. Yi,Tumber, Anthony,Tomlin, Kathy,Saville, Harry,Shehu, Erald,McAndrew, Craig,Carmichael, LeAnne,Bennett, James M.,Jeganathan, Fiona,Eve, Paul,Donovan, Adam,Hayes, Angela,Wood, Francesca,Raynaud, Florence I.,Fedorov, Oleg,Brennan, Paul E.,Burke, Rosemary,van Montfort, Rob L.M.,Rossanese, Olivia W.,Blagg, Julian,Bavetsias, Vassilios

supporting information, p. 316 - 337 (2019/06/05)

Residues in the histone substrate binding sites that differ between the KDM4 and KDM5 subfamilies were identified. Subsequently, a C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-one series was designed to rationally exploit these residue differences between

AZETIDINE DERIVATIVES

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Paragraph 0495; 0496; 0497; 0498; 0499; 0500, (2013/06/28)

Azetidine derivatives of which the following is exemplary and their use in the treatment of obesity, diabetes or dyslipidemia.

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