513-36-0

Usage

Uses

1. Used in Chemical Synthesis:
1-Chloro-2-methylpropane is used as a reagent for the preparation of organometallic compounds, specifically isobutyllithium, by reacting with lithium. This reaction is typically carried out using petroleum ether as a solvent. The resulting isobutyllithium compound is an important intermediate in organic synthesis, particularly for the formation of carbon-carbon bonds and the synthesis of various organic molecules.
2. Used in Analytical Chemistry:
The gas-solid virial coefficient of 1-chloro-2-methylpropane has been determined, which is essential for understanding its behavior under different pressure and temperature conditions. Additionally, the infrared and Raman spectra of 1-chloro-2-methylpropane have been studied, providing valuable information about its molecular structure and vibrational modes. These analytical techniques are crucial for the identification and characterization of 1-Chloro-2-methylpropane in various applications.

Purification Methods

Use the same methods as described under isoamyl chloride.[Beilstein 1 IV 287.]

InChI:InChI=1/C4H9Cl/c1-4(2)3-5/h4H,3H2,1-2H3

Upstream product

• 45019-19-0 phosphorochloridous acid diisobutyl ester 
• 78-83-1 2-methyl-propan-1-ol 
• 2465-56-7 methylene 
• 75-29-6 isopropyl chloride 
• 52057-41-7 dichlorophosphoric acid isobutyl ester 
• 13291-52-6 chlorosulfurous acid isobutyl ester 
• 75-28-5 Isobutane 
• 507-20-0 tertiary butyl chloride 
• 98070-93-0 trichlorophosphoranylidene-carbamic acid isobutyl ester 
• 78-81-9 isobutylamine 
• 56-23-5 tetrachloromethane 
• 110-05-4 di-tert-butyl peroxide 
• 78-77-3 Isobutyl bromide 
• 513-38-2 Isobutyl iodide 

Downstream Products

• 20600-62-8 Isobutylmercapto-essigsaeure 
• 585-34-2 3-tert-butylphenyol 
• 88-18-6 2-tert-Butylphenol 
• 3972-56-3 4-(tert-butyl)chlorobenzene 
• 253185-03-4 tert-butylbenzene 
• 1012-72-2 1,4-di-tert-butylbenzene 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 17980-47-1 isobutyltriethoxysilane 
• 624-38-4 para-diiodobenzene 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 18251-82-6 diisobutylamine hydrochloride 
• 115-11-7 isobutene 
• 2855-08-5 1-chloro-3,3-dimethylbutane 
• 1560-96-9 2-methyltridecane 

Relevant academic research and scientific papers

Method for co-producing methyl chloropropene and 2-chloro-2-methylpropane by chlorination of isobutene

The invention discloses a method for co-producing methyl chloropropene and 2-chloro-2-methylpropane by chlorination of isobutene. According to the method, a chlorination reaction is carried out on chlorine or a mixture of chlorine and inert gas and excessive isobutene to obtain products, namely methyl chloropropene and 2-chloro-2-methylpropane. The method can reduce influence of micro-mixing on arapid chlorination reaction of isobutene, decarburization and coking do not occur easily, and 2-chloro-2-methylpropane can be co-produced while the yield of methyl chloropropene is improved.

METHOD OF CONVERTING ALCOHOL TO HALIDE

The present invention relates to a method of converting an alcohol into a corresponding halide. This method comprises reacting the alcohol with an optionally substituted aromatic carboxylic acid halide in presence of an N-substituted formamide to replace a hydroxyl group of the alcohol by a halogen atom. The present invention also relates to a method of converting an alcohol into a corresponding substitution product. The second method comprises: (a) performing the method of the invention of converting an alcohol into the corresponding halide; and (b) reacting the corresponding halide with a nucleophile to convert the halide into the nucleophilic substitution product.

Synthesis of chlorothioformates from xanthates

The Vilsmeier reagent derived from N-formylmorpholine produces chlorothioformates from primary and secondary alkyl xanthates. The major side products are the corresponding alkyl chlorides. Secondary alkyl chlorothioformates give lower yields due to their instability. Treating xanthates with other common chlorinating agents (oxalyl chloride, thionyl chloride) gives only dialkyl thiodicarbonates. Georg Thieme Verlag Stuttgart.

PROCESS FOR MAKING HALOORGANOALKOXYSILANES

A haloorganoalkoxysilane is prepared by reacting an olefinic halide with an alkoxysilane in which the alkoxy group(s) contain at least two carbon atoms in a reaction medium to which has been added a catalytically effective amount of ruthenium-containing catalyst and a reaction-promoting effective amount of an electron-donating aromatic compound promoter. The process can be used to prepare, inter alia, chloropropyltriethoxysilane, which is a key intermediate in the manufacture of silane coupling agents.

Process for making haloorganoalkoxysilanes

A haloorganoalkoxysilane is prepared by reacting an olefinic halide with an alkoxysilane in which the alkoxy group(s) contain at least two carbon atoms in a reaction medium to which has been added a catalytically effective amount of ruthenium-containing catalyst and a reaction-promoting effective amount of an electron-donating aromatic compound promoter. The process can be used to prepare, inter alia, chloropropyltriethoxysilane, which is a key intermediate in the manufacture of silane coupling agents.

Gas-phase reactions of Cl atoms with propane, n-butane, and isobutane

Using the relative kinetic method, rate coefficients have been determined for the gas-phase reactions of chlorine atoms with propane, n-butane, and isobutane at total pressure of 100 Torr and the temperature range of 295-469 K. The Cl2 photolysis (λ = 420 nm) was used to generate Cl atoms in the presence of ethane as the reference compound. The experiments have been carried out using GC product analysis and the following rate constant expressions (in cm3 molecule-1 s-1) have been derived: (7.4 ±0.2) × 10-11 exp [-(70 ± 11)/T], Cl + C3H8 → HCl + CH3CH2CH2; (5.1 ± 0.5) × 10-11 exp [(104±32)/T], Cl + C3H8 → HCl + CH3CHCH3; (7.3±0.2) × 10-11 exp [-(68 ± 10)/T], Cl + n-C4H10 → HCl + CH3 CH2CH2CH2; (9.9 ± 2.2) × 10-11 exp [(106 ± 75)/T], Cl + n-C4H10 → HCl + CH3CH2CHCH3; (13.0 ± 1.8) × 10-11 exp [-(104 ± 50)/T], Cl + i-C4H10 → HCl + CH3CHCH3 CH2; (2.9 ± 0.5) × 10-11 exp [(155 ± 58)/T], Cl + i-C4H10 → HCl + CH3CCH3CH3 (all error bars are ±2ρ precision). The studies provide a set of reaction rate constants allowing to determine the contribution of competing hydrogen abstractions from primary, secondary, or tertiary carbon atom in alkane molecule.

Oxidative alkoxylation of zinc phosphide in alcoholic solutions of copper(II) chloride

Oxidative alkoxylation of Zn3P2 with the formation of valuable phosphoric and phosphorous acid esters occurred at a high rate and with a high selectivity in alcoholic solutions of CuCl2 under the action of oxygen at 30-60°C. Depending on the nature of the alcohol, two products were formed, namely, trialkyl phosphates (RO)3PO and dialkyl phosphites (RO)2HPO. Water favored the formation of dialkyl phosphates (RO)2(HO)PO. The kinetics and mechanism of the new catalytic reaction were studied, and the optimal conditions for conducting this reaction were found. The reaction proceeded in a topochemical mode by a separate redox mechanism.

Generation of alkyl hypochlorites in oxidation of alcohols with carbon tetrachloride catalyzed by vanadium and manganese compounds

Primary alcohols and diols with various structures were subjected to transformations into esters, aldehydes, ketones, and lactones under the action of carbon tetrachloride in the presence of manganese compounds (MnCl 2, MnO2, Mn(OAc)2, Mn(acac)3) and vanadium compounds (VCl5, V2O5, VO(acac) 2) as catalysts. These transformation proceeded with the involvement of alkyl hypochlorites, which were generated in the course of oxidation of alcohols with carbon tetrachloride catalyzed by manganese or vanadium compounds. The optimum molar ratios between the catalyst and reagents were determined, and the reaction conditions for the highly selective synthesis of esters, aldehydes, ketones, and lactones from alcohols were found.

Catalytic decomposition of alkyl chloroformates by hexabutylguanidinium chloride

Hexabutylguanidinium chloride (0.5 molar %) efficiently decomposes alkyl chloroformates into chlorides, with low alkenes formation, via a S(N)2 mechanism as demonstrated from substituents effects and asymmetric chloride synthesis.