223574-25-2

Upstream product

• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 4613-62-1 3-deoxy-1,2;5,6-di-O-isopropylidene-α-D-glucofuranoside 
• 158226-42-7 6-O-tert-butyldiphenylsilyl-3,5-dideoxy-5-iodo-1,2-O-isopropylidene-β-L-lyxo-hexofuranose 
• 158226-41-6 6-O-tert-butyldiphenylsilyl-3-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 4005-46-3 3-deoxy-1,2-O-isopropylidene-D-glucose 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 261155-73-1 Methyl (2E,4R,6S,7R)-8-tert-butyldiphenylsilyloxy-4,6-bis(triethylsilyloxy)-7-iodoct-2-enoate 

Relevant academic research and scientific papers

Radical cyclization of highly functionalized precursors: Stereocontrol of ring closure of acyclic 1-substituted-2,4-dihydroxylated hex-5-enyl radicals

Polysubstituted cyclopentane rings can be synthesized with good to high stereocontrol by radical cyclization using tributyltin hydride and a radical initiator, triethylborane-O2 in anhydrous xylene at room temperature. We have demonstrated that

C-furanoside synthesis via intramolecular cyclization

Polysubstituted C-furanoside 8, with the correct absolute configuration is readily available from diacetone-D-glucose. This C-furanoside after deprotection should be a useful synthon for natural product synthesis.