2236-41-1

Basic information

• Product Name: 2-iodo-4-methyl-1-(p-tolyloxy)benzene
• Synonyms: 2-iodo-4-methyl-1-(p-tolyloxy)benzene
• CAS NO: 2236-41-1
• Molecular Weight: 324.161
• Mol File: 2236-41-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-iodo-4-methyl-1-(p-tolyloxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-4-methyl-1-(p-tolyloxy)benzene(2236-41-1)
• EPA Substance Registry System: 2-iodo-4-methyl-1-(p-tolyloxy)benzene(2236-41-1)

Safety Data

• Hazardous Substances Data: 2236-41-1(Hazardous Substances Data)

Upstream product

• 446-11-7 4-fluoro-3-nitrotoluene 
• 106-44-5 p-cresol 
• 89-60-1 1-chloro-4-methyl-2-nitro-benzene 
• 1192-96-7 potassium p-cresolate 
• 2236-38-6 4-Methyl-1-(4-methylphenoxy)-2-nitrobenzene 
• 767222-91-3 5-Methyl-2-(4-methylphenoxy)benzenamine 

Relevant articles and documents

Four- and Sixfold Tandem-Domino Reactions Leading to Dimeric Tetrasubstituted Alkenes Suitable as Molecular Switches

A highly efficient palladium-catalyzed fourfold tandem-domino reaction consisting of two carbopalladation and two C-H-activation steps was developed for the synthesis of two types of tetrasubstituted alkenes 3 and 6 with intrinsic helical chirality starting from substrates 1 and 4, respectively. A sixfold tandem-domino reaction was also developed by including a Sonogashira reaction. 20 compounds with different substitution patterns were prepared with yields of up to 97%. Structure elucidation by X-ray crystallography confirmed helical chirality of the two alkene moieties. Photophysical investigations of some of the compounds showed pronounced switching properties through light-controlled changes of their stereochemical configuration.