223608-81-9Relevant academic research and scientific papers
A facile asymmetric synthesis of 1-substituted tetrahydroisoquinoline based on a chiral ligand-mediated addition of organolithium to imine
Taniyama, Daisuke,Hasegawa, Masayoshi,Tomioka, Kiyoshi
, p. 221 - 223 (1999)
A two-step methodology involving an asymmetric addition of organolithium to an imine and subsequent Moffat oxidation as the key steps provided a new synthetic way to the optically and biologically active 1-substituted tetrahydroisoquinolines.
