223608-83-1

Upstream product

• 223608-74-0 (4-Methoxy-phenyl)-[(R)-1-(2-vinyl-phenyl)-ethyl]-amine 
• 223608-81-9 2-{2-[(R)-1-(4-Methoxy-phenylamino)-ethyl]-phenyl}-ethanol 

Relevant academic research and scientific papers

A facile asymmetric synthesis of 1-substituted tetrahydroisoquinoline based on a chiral ligand-mediated addition of organolithium to imine

A two-step methodology involving an asymmetric addition of organolithium to an imine and subsequent Moffat oxidation as the key steps provided a new synthetic way to the optically and biologically active 1-substituted tetrahydroisoquinolines.