22362-63-6

Usage

Physical state

Yellow crystalline powder

Uses

a. Fragrance and flavoring agent in cosmetics and food products
b. Antioxidant in plastics and industrial applications
c. Ingredient in sunscreen, aftershave, and perfumes

Potential medicinal properties

a. Treatment of neurodegenerative diseases
b. Treatment of cancer

Chemical structure

Contains a tert-butyl group, a hydroxyl group, and a carbonyl group attached to a phenyl ring

Appearance

Yellow crystalline solid

Solubility

Soluble in organic solvents, such as ethanol and acetone

Stability

Stable under normal temperature and pressure conditions

Safety

Generally considered safe for use in cosmetics and food products, but potential for skin irritation or allergic reactions in some individuals

Upstream product

• 35154-02-0 ethyl 4-(tert-butyl)benzoate 

Downstream Products

• 22362-64-7 1-(3-bromo-5-tert-butyl-2-hydroxy-phenyl)-propan-1-one 
• 35155-04-5 2-propionyl-4-tert-butylanisole 
• 35237-84-4 2-Brom-4-tert-butyl-6-propionylanisol 
• 35155-08-9 2-Brom-4-tert-butyl-6-α-hydroxypropyl-anisol 
• 35155-06-7 4-tert-Butyl-2-α-hydroxypropyl-anisol 

Relevant academic research and scientific papers

2-Acyl-6-aminomethylphenol derivatives

A 2-acyl-6-aminomethylphenol derivative having the formula (I): STR1 wherein R1 represents a straight chain or branched chain alkyl group of 1 to 6 carbon atoms unsubstituted or substituted with 1 to 3 halogen atoms; a hydrogen atom or a group having the formula (II): wherein n represents 0 or an integer of 1 to 6; R7 represents a cycloalkyl group of 3 to 8 carbon atoms unsubstituted or substituted with at least one lower alkyl group; a phenyl group unsubstituted or substituted with at least one lower alkyl group, a halogen atom, a lower alkoxy group or a lower alkylthio group; a lower alkoxy group; a lower alkylthio group; a lower alkylsulfinyl group; a lower alkylsulfonyl group; an N-lower alkylamino group; an N,N-di-lower alkylamino group; or a pyridyl, furyl or thienyl group; R2 represents a straight chain or branched chain alkyl group of 1 to 6 carbon atoms; a cycloalkyl group of 4 to 8 carbon atoms unsubstituted or substituted with at least one lower alkyl group; a phenyl group unsubstituted or substituted with at least one lower alkyl group, a lower alkoxy group, a lower alkylthio group or a halogen atom; or a lower alkylthio group; R3 and R4 each represents a hydrogen atom or R2 and R3 or R2 and R4 when taken together represent an alkylene group of 2 to 5 carbon atoms unsubstituted or substituted with 1 or 2 lower alkyl groups; R5 represents a hydrogen atom or a lower alkyl group; and R6 represents a hydrogen atom, a lower alkyl group or an acyl group, and the pharmaceutically acceptable acid addition salt thereof having anti-inflammatory, analgesic, antipyretic, diuretic and hypotensive effects that can be used for preventing and curing diseases caused by inflammation, edema, hypertension, etc. are disclosed. Also disclosed is a process for preparing such derivative or a pharmaceutically acceptable acid addition salt thereof.