22364-29-0

Usage

Uses

Used in Pharmaceutical Industry:
2-bromo-4,5-dimethylbenzenamine is used as a building block for the synthesis of various pharmaceuticals due to its reactivity and the ability to form diverse chemical structures. Its incorporation into drug molecules can contribute to the development of new therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 2-bromo-4,5-dimethylbenzenamine is utilized as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity allows for the creation of compounds with specific properties tailored to target pests or weeds effectively while minimizing environmental impact.
Used in Dye Industry:
2-bromo-4,5-dimethylbenzenamine is employed as a key intermediate in the production of dyes, particularly those used in the textile and printing industries. Its unique chemical structure enables the development of dyes with specific color characteristics and improved fastness properties.
Used as a Reagent in Organic Synthesis:
Beyond its applications in specific industries, 2-bromo-4,5-dimethylbenzenamine serves as a versatile reagent in organic synthesis. Its reactivity allows chemists to use it in various reactions, leading to the formation of a wide range of compounds for research and commercial purposes.
It is crucial to handle and store 2-bromo-4,5-dimethylbenzenamine with care due to its potential toxicity and harmful effects if not managed properly. Proper safety measures and precautions should be taken to ensure the safe use of 2-broMo-4,5-diMethylbenzenaMine in various applications.

Upstream product

• 22364-28-9 N-(2-bromo-4,5-dimethylphenyl)acetamide 
• 2198-54-1 N-(3,4-dimethylphenyl)acetamide 
• 53938-24-2 1-bromo-4,5-dimethyl-2-nitrobenzene 
• 95-64-7 4-amino-o-xylene 
• 38899-22-8 1,2-dimethyl-4-nitrosobenzene 

Downstream Products

• 24932-48-7 1,2-dibromo-4,5-dimethylbenzene 
• 6514-63-2 2-bromo-4,5-dimethyl-benzonitrile 
• 116668-61-2 1,2-dibromo-3,5-dimethyl-benzene 
• 5100-97-0 1-bromo-2-fluoro-4,5-dimethylbenzene 
• 4612-57-1 2-bromo-4,5-dimethyl-benzoic acid 
• 854861-72-6 1,2-dibromo-3,5-dimethyl-4,6-dinitro-benzene 
• 1189351-13-0 C₆H₁₅N*C₉H₁₀BrNS₂ 
• 1195791-04-8 C₁₇H₁₉BrN₂ 
• 1195791-12-8 C₁₆H₁₇BrN₂ 
• 500536-40-3 1-bromo-2-chloro-4,5-dimethylbenzene 
• 937647-86-4 4-bromo-5-chlorophthalic acid 
• 887903-00-6 4,5-dimethyl-2-(trimethylsilylethynyl)aniline 

Relevant academic research and scientific papers

Para-Selective Halogenation of Nitrosoarenes with Copper(II) Halides

The para-selective direct bromination and chlorination of nitrosoarenes with copper(II) bromide and chloride is reported. Under mild reaction conditions, a range of halogenated arylnitroso compounds are obtained in moderate to good yields with high regioselectivity. Additionally, the versatility of the method is demonstrated by the development of a one-pot procedure to obtain the corresponding para-halogenated aniline- and nitrobenzene derivatives.

Selective halogen-lithium exchange of 1,2-dihaloarenes for successive [2+4] cycloadditions of arynes and isobenzofurans

Successive [2+4] cycloadditions of arynes and isobenzofurans by site-selective halogen-lithium exchange of 1,2-dihaloarenes were developed, allowing the rapid construction of polycyclic compounds which serve as a useful synthetic intermediates for the preparation of various polyacene derivatives.

ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS

Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.

4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides 4,4-(disubstituted)piperidine derivatives represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.

PIPERIDINE DERIVATIVES HAVING CCR3 ANTAGONISM

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C1-C6 alkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.