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223677-08-5

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223677-08-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 223677-08-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,6,7 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 223677-08:
(8*2)+(7*2)+(6*3)+(5*6)+(4*7)+(3*7)+(2*0)+(1*8)=135
135 % 10 = 5
So 223677-08-5 is a valid CAS Registry Number.

223677-08-5Downstream Products

223677-08-5Relevant articles and documents

Design and synthesis of thiol containing inhibitors of matrix metalloproteinases

Fink, Cynthia A.,Carlson, J. Eric,Boehm, Charles,McTaggart, Patricia,Qiao, Ying,Doughty, John,Ganu, Vishwas,Melton, Richard,Goldberg, Ronald

, p. 195 - 200 (2007/10/03)

A series of thiol containing derivatives was prepared. Several of these compounds were found to inhibit matrix metalloproteinases 1, 3, and 9 with selectivity towards 3 and 9. Compounds 15, 20 and 22 were administered to rats orally at 75 μmol/kg. Drug levels of compounds 20 and 22 in the plasma were found to exceed the IC50 values for MMP 3 and 9 four hours after administration.

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