223702-29-2

Upstream product

• 223702-27-0 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-5-tert-butyldiphenylsiloxy-2E,6E,10E,14E-hexadecatetraene 
• 223702-34-9 (3E,7E)-4,8,12-Trimethyl-2-[(E)-2-methyl-4-(tetrahydro-pyran-2-yloxy)-but-2-enyl]-2-trimethylsilanyloxy-trideca-3,7,11-trienenitrile 
• 223702-26-9 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-5-hydroxy-2E,6E,10E,14E-hexadecatetraene 
• 223702-24-7 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-2E,6E,10E,14E-hexadecatetraenyl-5-one 
• 223702-22-5 (3E,7E)-4,8,12-Trimethyl-2-trimethylsilanyloxy-trideca-3,7,11-trienenitrile 
• 180524-90-7 2-methyl-4-tetrahydropyranoxy-2-butenyl iodide 
• 156835-27-7 (E)-1-[(tetrahydro-2H-pyran-2-yl)oxy]-3-methyl-2-buten-4-ol 
• 502-67-0 Farnesal 
• 223719-21-9 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-14,15-epoxy-5-tert-butyldiphenylsiloxy-2E,6E,10E-hexadecatriene 

Downstream Products

• 223702-36-1 (6E,10E,14E)-12-(tert-Butyl-diphenyl-silanyloxy)-16-hydroxy-2,6,10,14-tetramethyl-hexadeca-6,10,14-trien-3-one 
• 223702-33-8 6-tert-butyldiphenylsiloxy-1E,3E,7E,11E-cembratetraene 
• 223702-31-6 3,7,11,15-tetramethyl-5-tert-butyldiphenylsiloxy-14-oxo-2E,6E,10E-hexadecatrienal 

Relevant academic research and scientific papers

The first total synthesis of preverecynarmin

Preverecynaimin, isolated from a pennatulatean coral, has been synthesized from E,E-farnesol.

The first total synthesis of preverecynarmin

Preverecynarmin, isolated from a pennatulacean coral, has been synthesized from E,E-famesol. The key steps are alkylation of the cyanohydrin trimethylsilyl ether 5 with the halide 6, the regioselective epoxidation of the siloxyl ether 9, and the intramolecular macrocyclization of the siloxyl ether 12 induced by Ti(0).