223702-29-2

Upstream product

• 223702-27-0 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-5-tert-butyldiphenylsiloxy-2E,6E,10E,14E-hexadecatetraene 
• 223702-34-9 (3E,7E)-4,8,12-Trimethyl-2-[(E)-2-methyl-4-(tetrahydro-pyran-2-yloxy)-but-2-enyl]-2-trimethylsilanyloxy-trideca-3,7,11-trienenitrile 
• 223702-26-9 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-5-hydroxy-2E,6E,10E,14E-hexadecatetraene 
• 223702-24-7 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-2E,6E,10E,14E-hexadecatetraenyl-5-one 
• 223702-22-5 (3E,7E)-4,8,12-Trimethyl-2-trimethylsilanyloxy-trideca-3,7,11-trienenitrile 
• 180524-90-7 2-methyl-4-tetrahydropyranoxy-2-butenyl iodide 
• 156835-27-7 (E)-1-[(tetrahydro-2H-pyran-2-yl)oxy]-3-methyl-2-buten-4-ol 
• 502-67-0 Farnesal 
• 223719-21-9 3,7,11,15-tetramethyl-1-tetrahydropyranoxy-14,15-epoxy-5-tert-butyldiphenylsiloxy-2E,6E,10E-hexadecatriene 

Downstream Products

• 223702-36-1 (6E,10E,14E)-12-(tert-Butyl-diphenyl-silanyloxy)-16-hydroxy-2,6,10,14-tetramethyl-hexadeca-6,10,14-trien-3-one 
• 223702-33-8 6-tert-butyldiphenylsiloxy-1E,3E,7E,11E-cembratetraene 
• 223702-31-6 3,7,11,15-tetramethyl-5-tert-butyldiphenylsiloxy-14-oxo-2E,6E,10E-hexadecatrienal 

Relevant academic research and scientific papers

The first total synthesis of preverecynarmin

Preverecynarmin, isolated from a pennatulacean coral, has been synthesized from E,E-famesol. The key steps are alkylation of the cyanohydrin trimethylsilyl ether 5 with the halide 6, the regioselective epoxidation of the siloxyl ether 9, and the intramolecular macrocyclization of the siloxyl ether 12 induced by Ti(0).

The first total synthesis of preverecynarmin

Preverecynaimin, isolated from a pennatulatean coral, has been synthesized from E,E-farnesol.