223704-20-9Relevant academic research and scientific papers
Chemoenzymatic syntheses of two optically active hexa-azamacrocycles
Alfonso, Ignacio,Rebolledo, Francisca,Gotor, Vicente
, p. 367 - 374 (2007/10/03)
Two optically active hexa-azamacrocycles with C2 and D2 symmetry, respectively, have been efficiently synthesized from the enzymatically prepared (R,R)-cyclohexane-1,2-diamine bis(amidoester) derivative (R,R)-4.
Sequential biocatalytic resolution of (±)-trans-cyclohexane-1,2-diamine. Chemoenzymatic synthesis of an optically active polyamine
Alfonso, Ignacio,Astorga, Covadonga,Rebolledo, Francisca,Gotor, Vicente
, p. 2471 - 2472 (2007/10/03)
Candida antarctica lipase-catalysed double monoaminolysis of dimethyl malonate by (±)-trans-cyclohexane-1,2-diamine allows the sequential resolution of the latter compound, affording an enantiopure bis(amidoester), (R,R)-3, which is subsequently transformed into an optically active polyamine, (R,R)-9.
