223708-55-2Relevant academic research and scientific papers
Strategy for the preparation of 2' and 3' branched nucleosides
Len,Postel,Mackenzie,Villa,Ronco
, p. 165 - 168 (1999)
1-(5-O-Benzyl-3-C-methylidene-2-oxo-3-deoxy-β-D-glycero-pentofuranosyl) thymine was prepared as the precursor of 2',3'-dibranched nucleosides in six steps from 5-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranose. This enone is the key starting compound for the preparation of a large series of potential antiretroviral agents against HIV-1.
