223754-37-8Relevant academic research and scientific papers
Approach to dual-acting platelet activating factor (PAF) receptor antagonist/thromboxane synthase inhibitor (TxSI) based on the link of PAF antagonists and TxSIs
Fujita, Masakazu,Seki, Taketsugu,Inada, Haruaki,Shimizu, Kazuhiro,Takahama, Akane,Sano, Tetsuro
, p. 341 - 344 (2007/10/03)
A series of compounds (22-36) which possess dual-acting PAF antagonist/TxSI have been generated by the approach of linking the known PAF antagonists and TxIs, such as Ridogrel (1).
Guanidine derivatives as combined thromboxane A2 receptor antagonists and synthase inhibitors
Soyka, Rainer,Guth, Brian D.,Weisenberger, Hans M.,Luger, Peter,Müller, Thomas H.
, p. 1235 - 1249 (2007/10/03)
A new series of ω-disubstituted alkenoic acid derivatives derived from samixogrel 5 were designed and synthesized as combined thromboxane A2 receptor antagonists/thromboxane A2 synthase inhibitors with improved solubility and reduced
